A Relationship between Serum Carcinoembryonic Antigen Concentrations and Job Titles of a Shipyard Workers

조선소 근로자의 직종과 혈청 암배아성 항원 농도와의 관련성

  • Jung, Kap Yeol (Department of Occupational and Environmental Medicine, School of Medicine, Dong-A University) ;
  • Kim, Jung Won (Department of Occupational & Environmental Medicine, College of Medicine, Kosin University) ;
  • Ye, Byeong Jin (Department of Occupational & Environmental Medicine, College of Medicine, Kosin University)
  • 정갑열 (동아대학교 의과대학 직업환경의학교실) ;
  • 김정원 (고신대학교 의과대학 직업환경의학교실) ;
  • 예병진 (고신대학교 의과대학 직업환경의학교실)
  • Published : 2013.06.30

Abstract

Objectives: The purpose of this study was to clarify the association between serum carcinoembryonic antigen (CEA) and type of work in the shipbuilding industry. Methods: 1,072 final study subjects were admitted to a general hospital from April through July 2010 for the purpose of medical examination. Data on general characteristics such as age, smoking history, alcohol history and exercise habits was gathered through structured self-administered questionnaires. Information on job factors was collected from a medical examination, by interview and through company personnel data. Serum CEA levels were measured after eight hours' fasting and were analyzed by a radioimmunoassay. Results: On univariate analysis, the mean serum CEA level was significantly higher among married (p=0.02), older age (p<0.01), longer work time (p<0.01), smokers (p<0.01), lower education (p<0.01), and indirect and direct exposure groups (p<0.01). On multiple regression analysis, serum CEA level was influenced by smoking (p=0.001), duration of work (p=0.019), and direct exposure group (p<0.001). However, among the direct exposure group, serum CEA level was not significantly different between welding, mounting, electro-device constructive work, grinding and cleaning, and painting. Conclusions: The goal of this research was to determine if there were differences between serum CEA levels according to occupational role among shipyard workers. The direct exposure group of shipyard workers had a relatively higher level of serum CEA than did the indirect exposure group and office workers, most likely due to occupational exposure.

Keywords

References

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