DOI QR코드

DOI QR Code

Isolated Post-Transplantation Lymphoproliferative Disease Involving the Breast and Axilla as Peripheral T-cell Lymphoma

  • Hwang, Ji-Young (Department of Radiology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Cha, Eun Suk (Department of Radiology, Ewha Womans University School of Medicine) ;
  • Lee, Jee Eun (Department of Radiology, Ewha Womans University School of Medicine) ;
  • Sung, Sun Hee (Department of Pathology, Ewha Womans University School of Medicine)
  • 투고 : 2013.01.17
  • 심사 : 2013.02.25
  • 발행 : 2013.09.01

초록

Post-transplantation lymphoproliferative disorders (PTLDs) are a heterogeneous group of diseases that represent serious complications following immunosuppressive therapy for solid organ or hematopoietic-cell recipients. In contrast to B-cell PTLD, T-cell PTLD is less frequent and is not usually associated with Epstein Barr Virus infection. Moreover, to our knowledge, isolated T-cell PTLD involving the breast is extremely rare and this condition has never been reported previously in the literature. Herein, we report a rare case of isolated T-cell PTLD of the breast that occurred after a patient had been treated for allogeneic peripheral blood stem cell transplantation due to acute myeloblastic leukemia.

키워드

참고문헌

  1. Abhyankar SH, Chiang KY, McGuirk JP, Pati AR, Godder KT, Welsh JA, et al. Late onset Epstein-Barr virus-associated lymphoproliferative disease after allogeneic bone marrow transplant presenting as breast masses. Bone Marrow Transplant 1998;21:295-297 https://doi.org/10.1038/sj.bmt.1701070
  2. Au WY, Lie AK, Lee CK, Ma SK, Wan TS, Shek TW, et al. Late onset post-transplantation lymphoproliferative disease of recipient origin following cytogenetic relapse and occult autologous haematopoietic regeneration after allogeneic bone marrow transplantation for acute myeloid leukaemia. Bone Marrow Transplant 2001;28:417-419 https://doi.org/10.1038/sj.bmt.1703144
  3. Baker KS, DeFor TE, Burns LJ, Ramsay NK, Neglia JP, Robison LL. New malignancies after blood or marrow stem-cell transplantation in children and adults: incidence and risk factors. J Clin Oncol 2003;21:1352-1358 https://doi.org/10.1200/JCO.2003.05.108
  4. Coy DL, Ormazabal A, Godwin JD, Lalani T. Imaging evaluation of pulmonary and abdominal complications following hematopoietic stem cell transplantation. Radiographics 2005;25:305-317; discussion 318 https://doi.org/10.1148/rg.252045037
  5. Ibrahim HA, Menasce LP, Pomplun S, Burke M, Bower M, Naresh KN. Presence of monoclonal T-cell populations in B-cell post-transplant lymphoproliferative disorders. Mod Pathol 2011;24:232-240 https://doi.org/10.1038/modpathol.2010.186
  6. Leblond V, Dhedin N, Mamzer Bruneel MF, Choquet S, Hermine O, Porcher R, et al. Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders. J Clin Oncol 2001;19:772-778
  7. Socié G, Curtis RE, Deeg HJ, Sobocinski KA, Filipovich AH, Travis LB, et al. New malignant diseases after allogeneic marrow transplantation for childhood acute leukemia. J Clin Oncol 2000;18:348-357
  8. Yin CC, Medeiros LJ, Abruzzo LV, Jones D, Farhood AI, Thomazy VA. EBV-associated B- and T-cell posttransplant lymphoproliferative disorders following primary EBV infection in a kidney transplant recipient. Am J Clin Pathol 2005;123:222-228 https://doi.org/10.1309/PH2BK79HAVTTPW13
  9. Awaya N, Adachi A, Mori T, Kamata H, Nakahara J, Yokoyama K, et al. Fulminant Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder with hemophagocytosis following autologous peripheral blood stem cell transplantation for relapsed angioimmunoblastic T-cell lymphoma. Leuk Res 2006;30:1059-1062 https://doi.org/10.1016/j.leukres.2005.10.022
  10. Borhani AA, Hosseinzadeh K, Almusa O, Furlan A, Nalesnik M. Imaging of posttransplantation lymphoproliferative disorder after solid organ transplantation. Radiographics 2009;29:981- 1000; discussion 1000-1002 https://doi.org/10.1148/rg.294095020
  11. Schramm N, Pfluger T, Reiser MF, Berger F. Subcutaneous panniculitis-like T-cell lymphoma with breast involvement: functional and morphological imaging findings. Br J Radiol 2010;83:e90-e94 https://doi.org/10.1259/bjr/69172676
  12. von Falck C, Maecker B, Schirg E, Boerner AR, Knapp WH, Klein C, et al. Post transplant lymphoproliferative disease in pediatric solid organ transplant patients: a possible role for [18F]-FDG-PET(/CT) in initial staging and therapy monitoring. Eur J Radiol 2007;63:427-435 https://doi.org/10.1016/j.ejrad.2007.01.007
  13. Kiresi DA, Kivrak AS, Ecirli S, Toy H. Secondary breast, pancreatic, and renal involvement with non-Hodgkin's lymphoma: imaging findings. Breast 2006;15:106-110 https://doi.org/10.1016/j.breast.2004.11.008
  14. Liberman L, Giess CS, Dershaw DD, Louie DC, Deutch BM. Non- Hodgkin lymphoma of the breast: imaging characteristics and correlation with histopathologic findings. Radiology 1994;192:157-160 https://doi.org/10.1148/radiology.192.1.8208929
  15. Yang WT, Lane DL, Le-Petross HT, Abruzzo LV, Macapinlac HA. Breast lymphoma: imaging findings of 32 tumors in 27 patients. Radiology 2007;245:692-702 https://doi.org/10.1148/radiol.2452061726

피인용 문헌

  1. Burkitt-like post-transplant lymphoproliferative disorder (PTLD) presenting with breast mass in a renal transplant recipient: a report of a rare case vol.93, pp.12, 2014, https://doi.org/10.1007/s00277-014-2094-0
  2. Primary Breast Lymphoma in an Immunocompromised Male Patient: A Case Report vol.73, pp.4, 2015, https://doi.org/10.3348/jksr.2015.73.4.264
  3. Donor-derived mycosis fungoides following reduced intensity haematopoietic stem cell transplantation from a matched unrelated donor vol.2017, pp.jan_310, 2013, https://doi.org/10.1136/bcr-2016-216331