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발진열 심근염의 늦은 회복기에 발생한 완전방실전도차단 1예

Delayed-Onset Complete Atrioventricular Block in a Patient with Murine Typhus Myocarditis

  • 김보성 (동아대학교 의과대학 내과학교실) ;
  • 김수영 (동아대학교 의과대학 내과학교실) ;
  • 한승희 (동아대학교 의과대학 내과학교실) ;
  • 박혜경 (동아대학교 의과대학 내과학교실) ;
  • 이동현 (동아대학교 의과대학 내과학교실) ;
  • 박종성 (동아대학교 의과대학 내과학교실)
  • Kim, Bo Sung (Department of Internal Medicine, Dong-A University College of Medicine) ;
  • Kim, Su Young (Department of Internal Medicine, Dong-A University College of Medicine) ;
  • Han, Seung Hee (Department of Internal Medicine, Dong-A University College of Medicine) ;
  • Park, He Kyung (Department of Internal Medicine, Dong-A University College of Medicine) ;
  • Lee, Dong Hyun (Department of Internal Medicine, Dong-A University College of Medicine) ;
  • Park, Jong Sung (Department of Internal Medicine, Dong-A University College of Medicine)
  • 투고 : 2012.06.24
  • 심사 : 2012.09.12
  • 발행 : 2013.05.01

초록

2개월간의 발열을 주소로 입원한 62세의 여자 환자가 발진열로 진단받고 doxycycline 치료 후 회복되어 퇴원하였으나 6-8주 후부터 어지럼증 및 운동 시 호흡곤란이 발생하였으며 좌각차단 형태의 넓은 QRS파 이탈율동을 동반한 완전방실차단이 확인되었다. 심근 트로포닌-I 수치의 지속적인 상승과 특징적인 심장자기공명영상 소견에 따라 아급성 심근염 및 염증 후 섬유화에 의해 유발된 완전방실전도차단으로 진단하였으며, 방실전도차단이 지속되어 영구형 인공심박 조율기를 삽입하여 치료하였다. 발진열은 리케차티피에 의해 유발되는 벼룩매개 감염 질환이며 드물지만 발진열의 급성 파종기에 심근염 등의 합병증이 발생하는 것으로 보고되었다. 저자들은 리케차티피 감염 후 발생한 심근염과 염증 후 섬유화에 의해 늦은 회복기에 발생한 완전방실전도차단을 경험하였으며 이를 문헌고찰과 함께 보고하는 바이다.

Murine typhus is a flea-borne infectious disease caused by Rickettsia typhi, of which myocarditis is a rare complication in the acute disseminating phase. A 62-year-old female presented with a fever and was diagnosed with murine typhus. She was treated with doxycycline and discharged after complete resolution of the fever. However, recurrent presyncope and exertional dyspnea developed 6-8 weeks later. Complete atrioventricular (AV) block with a wide QRS escape rhythm and a left bundle branch block configuration was documented. Subacute myocarditis was diagnosed based on persistent cardiac troponin-I elevation and typical cardiac magnetic resonance imaging findings. A permanent pacemaker was implanted for symptomatic complete AV block. Few reports of myocarditis in murine typhus have been published. We report a case of murine typhus myocarditis complicated by complete AV block in the late convalescence phase.

키워드

참고문헌

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