Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Therapeutic Effect of a Sodium Salt Mixture Against Salmonella gallinarum Infection in Broiler

복합나트륨염의 Salmonella gallinarum 감염 육계에 대한 치료효과

  • Lee, Yeo Eun (Department of Environmental Health, Graduate School of Public Health, Gyeongsang National University) ;
  • Cha, Chun Nam (Engineering Research Institute, Department of Industrial Systems Engineering, Gyeongsang National University) ;
  • Son, Song Ee (Research Institute of Life Sciences, College of Veterinary Medicine, Gyeongsang National University) ;
  • Yoo, Chang-Yeul (Department of Computer Information, Gyeongnam Provincial Namhae College) ;
  • Park, Eun-Kee (Department of Medical Humanities and Social Medicine, College of Medicine, Kosin University) ;
  • Kim, Suk (Research Institute of Life Sciences, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hu Jang (Department of Environmental Health, Graduate School of Public Health, Gyeongsang National University)
  • 이여은 (경상대학교 보건대학원 환경보건학과) ;
  • 차춘남 (경상대학교 산업시스템공학부 공학연구원) ;
  • 손송이 (경상대학교 수의과대학.생명과학연구소) ;
  • 유창열 (경남도립남해대학 인터넷정보학과) ;
  • 박은기 (고신대학교 의과대학 인문사회의학과) ;
  • 김석 (경상대학교 수의과대학.생명과학연구소) ;
  • 이후장 (경상대학교 보건대학원 환경보건학과)
  • Accepted : 2011.12.19
  • Published : 2013.02.28
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Abstract

The objectives in the present study were to evaluate the therapeutic effect of a sodium salts mixture against Salmonella gallinarum infection in broiler. Of this study, sixty broilers at two weeks of age (body weight, $450{\pm}35$ g) were used to estimate the efficacy of a sodium salts mixture (3.25 mg sodium azide, 2.45 mg sodium cyanide, 0.8 g sodium chlorate) against Salmonella gallinarum infection in broiler with drinking water. Broilers challenged with S. gallinarum were administered with ${\times}$ 1(group I) and ${\times}$ 2(group II) sodium salt mixture for seven days, and cecal content samples were collected at the gate of treatment and on 1st, 3rd, 5th, and 7th day after administration. Changes in body weight and cecal shedding of S. gallinarum were monitored during the experimental period. All groups treated with the sodium salt mixture slightly increased body weight compared to control group but there is no significant difference. At 7th day after administration, the number of S. gallinarum in group I and II was significantly decreased compared to control group (p < 0.001). In the hematological and blood biochemical analysis, values of parameters were not significantly different between the treated groups and control group. From results of the present study, the sodium salt mixture had therapeutic effect on S. gallinarum infection in broilers.

Keywords

References

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