Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Skeletal Manifestations of Hydatid Disease in Serbia: Demographic Distribution, Site Involvement, Radiological Findings, and Complications

  • Bracanovic, Djurdja (Laboratory for Anthropology, Institute of Anatomy, School of Medicine, University of Belgrade) ;
  • Djuric, Marija (Laboratory for Anthropology, Institute of Anatomy, School of Medicine, University of Belgrade) ;
  • Sopta, Jelena (Institute of Pathology, School of Medicine, University of Belgrade) ;
  • Djonic, Danijela (Laboratory for Anthropology, Institute of Anatomy, School of Medicine, University of Belgrade) ;
  • Lujic, Nenad (Institute for Orthopedic Surgery "Banjica")
  • Received : 2013.03.10
  • Accepted : 2013.07.05
  • Published : 2013.08.31
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Abstract

Although Serbia is recognized as an endemic country for echinococcosis, no information about precise incidence in humans has been available. The aim of this study was to investigate the skeletal manifestations of hydatid disease in Serbia. This retrospective study was conducted by reviewing the medical database of Institute for Pathology (Faculty of Medicine in Belgrade), a reference institution for bone pathology in Serbia. We reported a total of 41 patients with bone cystic echinococcosis (CE) during the study period. The mean age of 41 patients was $40.9{\pm}18.8$ years. In 39% of patients, the fracture line was the only visible radiological sign, followed by cyst and tumefaction. The spine was the most commonly involved skeletal site (55.8%), followed by the femur (18.6%), pelvis (13.9%), humerus (7.0%), rib (2.3%), and tibia (2.3%). Pain was the symptom in 41.5% of patients, while some patients demonstrated complications such as paraplegia (22.0%), pathologic fracture (48.8%), and scoliosis (9.8%). The pathological fracture most frequently affected the spine (75.0%) followed by the femur (20.0%) and tibia (5.0%). However, 19.5% of patients didn't develop any complication or symptom. In this study, we showed that bone CE is not uncommon in Serbian population. As reported in the literature, therapy of bone CE is controversial and its results are poor. In order to improve the therapy outcome, early diagnosis, before symptoms and complications occur, can be contributive.

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References

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