Annals of Clinical Neurophysiology

  • 제15권2호
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  • Pages.42-47
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  • 2013
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  • 2508-691X(pISSN)
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  • 2508-6960(eISSN)
대한임상신경생리학회 (The Korean Society of Clinical Neurophysiology)
권호 표지

급성 저산소뇌병증의 예후 예측인자로서 확산강조영상의 역할

Role of Diffusion-Weighted Imaging as a Prognostic Indicator in Acute Hypoxic Encephalopathy

  • 김진수 (서울대학교 의과대학 신경과학교실) ;
  • 노원영 (서울대학교 의과대학 신경과학교실) ;
  • 임재성 (서울특별시보라매병원 신경과) ;
  • 김선정 (하워드힐병원 신경과) ;
  • 윤창호 (서울대학교 의과대학 신경과학교실) ;
  • 박성호 (서울대학교 의과대학 신경과학교실)
  • Kim, Jin-Soo (Department of Neurology, Seoul National University College of Medicine) ;
  • Noh, Won-Young (Department of Neurology, Seoul National University College of Medicine) ;
  • Lim, Jae-Sung (Department of Neurology, Seoul National University Boramae Hospital) ;
  • Kim, Seon-Jeong (Department of Neurology, Howard Hill Hospital) ;
  • Yun, Chang-Ho (Department of Neurology, Seoul National University College of Medicine) ;
  • Park, Seong-Ho (Department of Neurology, Seoul National University College of Medicine)
  • 투고 : 2013.01.14
  • 심사 : 2013.08.16
  • 발행 : 2013.12.30
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초록

Background: Diffusion-weighted image (DWI) might be useful to predict the prognosis of acute hypoxic encephalopathy. The aim of our study was to test whether the early change and extent of DWI abnormalities can be an indicator of the clinical outcome of hypoxic encephalopathy. Methods: Forty-four patients who were diagnosed as hypoxic encephalopathy due to the cardiorespiratory arrest were retrospectively identified. Clinical variables were determined, and the DWI abnormalities were counted by four areas: cortex, subcortical white matter, cerebellum and deep grey matter, and were divided into three groups by the extent of lesions. Prognosis was classified as 'poor' (Glasgow coma scale (GSC) at 30 days after arrest <9 or death) and 'good' (GSC at 30 days after arrest ${\geq}9$). Results: GCS at day 3 (p<0.001), presence of seizure (p=0.01), and presence of lesion (p<0.001) were significantly different in prognosis, but statistically there is no association with the extent of lesions and prognosis (p=0.26). Conclusions: Presence of early DWI changes could predict the clinical outcome of hypoxic encephalopathy after cardiorespiratory arrest.

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참고문헌

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