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Complications Leading Reoperation after Gastrectomy in Patients with Gastric Cancer: Frequency, Type, and Potential Causes

  • Yi, Ha Woo (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Su Mi (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Sang Hyun (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Shim, Jung Ho (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Min Gew (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Jun Ho (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Noh, Jae Hyung (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Sohn, Tae Sung (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Bae, Jae Moon (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Sung (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2013.09.23
  • Accepted : 2013.11.13
  • Published : 2013.12.30

Abstract

Purpose: Reoperations after gastrectomy for gastric cancer are performed for many types of complications. Unexpected reoperations may cause mental, physical, and financial problems for patients. The aim of the present study was to evaluate the causes of reoperations and to develop a strategic decision-making process for these reoperations. Materials and Methods: From September 2002 through August 2010, 6,131 patients underwent open conventional gastrectomy operations at Samsung Medical Center. Of these, 129 patients (2.1%) required reoperation because of postoperative complications. We performed a retrospective analysis of the patients using an electronic medical record review. Statistical data were analyzed to compare age, sex, stage, type of gastrectomy, length of operation, size of tumor, and number of lymph node metastasis between patients who had been operated and those who had not. Results: The variables of age, sex, tumor stage, type of gastrectomy, length of operation, and number of lymph node metastases did not differ between the 2 groups. However, the mean tumor size in the reoperation group was greater than that in the non-reoperation group ($5.0{\pm}3.7$ [standard deviation] versus $4.1{\pm}2.9$, P=0.007). The leading cause of reoperation was surgical-site infection (n=49, 0.79%). Patients with intra-abdominal bleeding were operated on again in the shortest period after the initial gastrectomy ($6.3{\pm}4.2$ days). Patients with incisional hernia were not reoperated on until after $208.3{\pm}81.0$ days, the longest postoperative period. Conclusions: Tumor size was the major variable leading to reoperation after gastrectomy for gastric cancer. The most common complication requiring the reoperation was a surgical site-related complication.

Keywords

References

  1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127:2893-2917. https://doi.org/10.1002/ijc.25516
  2. Jung KW, Won YJ, Kong HJ, Oh CM, Seo HG, Lee JS. Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010. Cancer Res Treat 2013;45:1-14. https://doi.org/10.4143/crt.2013.45.1.1
  3. McCulloch P, Niita ME, Kazi H, Gama-Rodrigues JJ. Gastrectomy with extended lymphadenectomy for primary treatment of gastric cancer. Br J Surg 2005;92:5-13. https://doi.org/10.1002/bjs.4839
  4. Ichikawa D, Kurioka H, Yamaguchi T, Koike H, Okamoto K, Otsuji E, et al. Postoperative complications following gastrectomy for gastric cancer during the last decade. Hepatogastroenterology 2004;51:613-617.
  5. Aoki M, Saka M, Morita S, Fukagawa T, Katai H. Afferent loop obstruction after distal gastrectomy with Roux-en-Y reconstruction. World J Surg 2010;34:2389-2392. https://doi.org/10.1007/s00268-010-0602-5
  6. Wu CW, Chang IS, Lo SS, Hsieh MC, Chen JH, Lui WY, et al. Complications following D3 gastrectomy: post hoc analysis of a randomized trial. World J Surg 2006;30:12-16. https://doi.org/10.1007/s00268-005-7951-5
  7. Oh SJ, Choi WB, Song J, Hyung WJ, Choi SH, Noh SH; Yonsei Gastric Cancer Clinic. Complications requiring reoperation after gastrectomy for gastric cancer: 17 years experience in a single institute. J Gastrointest Surg 2009;13:239-245. https://doi.org/10.1007/s11605-008-0716-3
  8. Japanese Gastric Cancer Association. Japanese Classification of Gastric Carcinoma - 2nd English Edition. Gastric Cancer 1998;1:10-24. https://doi.org/10.1007/PL00011681
  9. Sano T, Aiko T. New Japanese classifications and treatment guidelines for gastric cancer: revision concepts and major revised points. Gastric Cancer 2011;14:97-100. https://doi.org/10.1007/s10120-011-0040-6
  10. Li QG, Li P, Tang D, Chen J, Wang DR. Impact of postoperative complications on long-term survival after radical resection for gastric cancer. World J Gastroenterol 2013;19:4060-4065. https://doi.org/10.3748/wjg.v19.i25.4060
  11. Kelly KJ, Allen PJ, Brennan MF, Gollub MJ, Coit DG, Strong VE. Internal hernia after gastrectomy for cancer with Roux-Y reconstruction. Surgery 2013;154:305-311. https://doi.org/10.1016/j.surg.2013.04.027
  12. Luijendijk RW, Lemmen MH, Hop WC, Wereldsma JC. Incisional hernia recurrence following "vest-over-pants" or vertical Mayo repair of primary hernias of the midline. World J Surg 1997;21:62-65. https://doi.org/10.1007/s002689900194
  13. Mäkelä JT, Kiviniemi H, Juvonen T, Laitinen S. Factors influencing wound dehiscence after midline laparotomy. Am J Surg 1995;170:387-390. https://doi.org/10.1016/S0002-9610(99)80309-2
  14. Israelsson LA, Jonsson T. Suture length to wound length ratio and healing of midline laparotomy incisions. Br J Surg 1993;80:1284-1286. https://doi.org/10.1002/bjs.1800801020
  15. Osther PJ, Gjøde P, Mortensen BB, Mortensen PB, Bartholin J, Gottrup F. Randomized comparison of polyglycolic acid and polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing. Br J Surg 1995;82:1080-1082. https://doi.org/10.1002/bjs.1800820824
  16. Sano T, Sasako M, Yamamoto S, Nashimoto A, Kurita A, Hiratsuka M, et al. Gastric cancer surgery: morbidity and mortality results from a prospective randomized controlled trial comparing D2 and extended para-aortic lymphadenectomy- -Japan Clinical Oncology Group study 9501. J Clin Oncol 2004;22:2767-2773. https://doi.org/10.1200/JCO.2004.10.184
  17. Mittermair R, Sucher R, Perathoner A. Results and complications after laparoscopic sleeve gastrectomy. Surg Today 2013 [Epub ahead of print].

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