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A Case of Immunoglobulin A Nephropathy in a Patient with Kimura's Disease

  • Park, Hye Jung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Jae Kyung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Hyun Ju (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Kwan-Kyu (Department of Pathology, School of Medicine, Catholic University of Daegu) ;
  • Bae, Yoon Sung (Department of Pathology, Yonsei University College of Medicine) ;
  • Lee, Yong Kyu (Nephrology Division, Internal Medicine Department, National Health Institute Corporation, Ilsan Hospital) ;
  • Kim, Beom Seok (Nephrology Division, Internal Medicine Department, Severance Hospital, Yonsei University College of Medicine)
  • Received : 2013.06.19
  • Accepted : 2013.07.12
  • Published : 2013.12.31

Abstract

Kimura's disease is an angiolymphoid-proliferative disorder that manifests with benign subcutaneous swelling predominantly in the head and the neck. Kidney involvement, including proteinuria, occurs in 12-16% of patients with the disease, and 60-78% of such cases is nephrotic syndrome. Reported etiologies of nephrotic syndrome in Kimura's disease include membranous glomerulonephritis, mesangial proliferative glomerulonephritis, minimal-change disease, focal segmental glomerulosclerosis, diffuse proliferative glomerulonephritis and immunoglobulin A (IgA) nephropathy. There have been only two case reports of IgA nephropathy in Kimura's disease, in 1998. In this report, we present a third case of IgA nephropathy associated with Kimura's disease.

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