Mass Spectrometry Letters

Korean Society for Mass Spectrometry (한국질량분석학회)
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Simulation Study to Improve Ion Transmission Efficiency in Mass Spectrometry with a Dual Ion Funnel Ion Source

  • Baek, Sun Jong (Division of Mass Spectrometry Research, Korea Basic Science Institute) ;
  • Kim, Seung Yong (Division of Mass Spectrometry Research, Korea Basic Science Institute) ;
  • Kim, Taeman (MS Development Group, Genomic System Research Center, Bioneer Corporation) ;
  • Kim, Hyun Sik (Division of Mass Spectrometry Research, Korea Basic Science Institute)
  • Received : 2013.12.17
  • Accepted : 2013.12.24
  • Published : 2013.12.30
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Abstract

We performed computer simulations to improve transmission efficiencies of a dual ion funnel system implemented on an FT-ICR MS. We found that the low m/z range from 50 to 150 could be significantly improved by operating the two ion funnels at different RF amplitudes. These new operational conditions could be applied to analyze metabolome samples, which require high sensitivity in the m/z range from 50 to 1,000.

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References

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