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A Case of Spontaneous Remission of Acute Pulmonary Embolism

자연 소실된 급성 폐색전증 1예

  • Lee, Jae-Joon (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Lee, Min-Ji (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Park, Hyo (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Zeon, Seok-Jae (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Lim, Young-Min (Department of Internal Medicine, Gumi CHA Hospital, CHA University College of Medicine) ;
  • Song, Sang-Hee (Department of Internal Medicine, Gumi CHA Hospital, CHA University College of Medicine) ;
  • Na, Dong-Jib (Department of Internal Medicine, Gumi CHA Hospital, CHA University College of Medicine) ;
  • Kim, Eun-Jin (Department of Internal Medicine, Gumi CHA Hospital, CHA University College of Medicine)
  • 이재준 (을지대학교 의과대학 내과학교실) ;
  • 이민지 (을지대학교 의과대학 내과학교실) ;
  • 박효 (을지대학교 의과대학 내과학교실) ;
  • 전석재 (을지대학교 의과대학 내과학교실) ;
  • 임영민 (차의과학대학교 구미차병원 내과학교실) ;
  • 송상희 (차의과학대학교 구미차병원 내과학교실) ;
  • 나동집 (차의과학대학교 구미차병원 내과학교실) ;
  • 김은진 (차의과학대학교 구미차병원 내과학교실)
  • Received : 2011.09.27
  • Accepted : 2011.10.25
  • Published : 2012.02.29

Abstract

Acute pulmonary embolism (PE) ranges from asymptomatic to often fatal, incidentally discovered emboli to massive embolism causing immediate death. Acute PE may occur rapidly and unpredictably and may be difficult to diagnose. Mortality and complications can be reduced by prompt diagnosis and therapy. Untreated PE is associated with a mortality rate of approximately 30 percents. Most patients with PE have endogenous fibrinolysis, although it is not effective enough to prevent PE. A case of spontaneous remission of untreated acute PE has not previously been reported. Here we present a case of spontaneously resolved acute PE without any treatment.

Keywords

References

  1. Park YS, Ha JW, Kwon KH, Jang YS, Chung NS, Shim WH, et al. Clinical characteristics and predictors of in-hospital mortality for patients with acute major pulmonary embolism. Korean J Med 2000;58:293-300.
  2. Tapson VF. Acute pulmonary embolism. N Engl J Med 2008;358:1037-52. https://doi.org/10.1056/NEJMra072753
  3. Carson JL, Kelley MA, Duff A, Weg JG, Fulkerson WJ, Palevsky HI, et al. The clinical course of pulmonary embolism. N Engl J Med 1992;326:1240-5. https://doi.org/10.1056/NEJM199205073261902
  4. Nijkeuter M, Hovens MM, Davidson BL, Huisman MV. Resolution of thromboemboli in patients with acute pulmonary embolism: a systematic review. Chest 2006; 129:192-7. https://doi.org/10.1378/chest.129.1.192
  5. Goldhaber SZ. Pulmonary embolism. In: Bonow RO, Mann DL, Zipes DP, Libby P, Braunwald E, editors. Braunwald's heart disease: a textbook of cardiovascular medicine. 9th ed. Philadelphia: Saunders; 2012. p.1679-95.
  6. Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galie N, Pruszczyk P, et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 2008;29:2276-315. https://doi.org/10.1093/eurheartj/ehn310
  7. Yong HS. MDCT application in the Vascular System. J Korean Med Assoc 2007;50:25-32. https://doi.org/10.5124/jkma.2007.50.1.25
  8. Aujesky D, Obrosky DS, Stone RA, Auble TE, Perrier A, Cornuz J, et al. Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med 2005;172:1041-6. https://doi.org/10.1164/rccm.200506-862OC
  9. Choi WH, Kwon SU, Jwa YJ, Kim JA, Choi YH, Chang JH, et al. The pulmonary embolism severity index in predicting the prognosis of patients with pulmonary embolism. Korean J Intern Med 2009;24:123-7. https://doi.org/10.3904/kjim.2009.24.2.123
  10. Gans H, Rosenberg M, Tan BH, Boulton A. The mechanism of spontaneous resolution of thromboemboli. Surg Gynecol Obstet 1970;130:326-32.
  11. Wilson JE 3rd, Frenkel EP, Pierce AK, Johnson RL Jr, Winga ER, Curry GC, et al. Spontaneous fibrinolysis in pulmonary embolism. J Clin Invest 1971;50:474-80. https://doi.org/10.1172/JCI106515
  12. Walker RH, Goodwin J, Jackson JA. Resolution of pulmonary embolism. Br Med J 1970;4:135-9. https://doi.org/10.1136/bmj.4.5728.135
  13. Geerts WH, Heit JA, Clagett GP, Pineo GF, Colwell CW, Anderson FA Jr, et al. Prevention of venous thromboembolism. Chest 2001;119(1 Suppl):132S-75S. https://doi.org/10.1378/chest.119.1_suppl.132S
  14. Shinohara Y, Nishimaru K, Sawada T, Terashi A, Handa S, Hirai S, et al. Sarpogrelate-aspirin comparative clinical study for efficacy and safety in secondary prevention of cerebral infarction (S-ACCESS): a randomized, double-blind, aspirin-controlled trial. Stroke 2008;39: 1827-33. https://doi.org/10.1161/STROKEAHA.107.505131