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비결핵성 항산균증과 유사한 방사선학적 소견을 보이는 환자에서 Segniliparus rugosus가 동정된 첫 증례

First Isolation of Segniliparus rugosus from a Patient with Radiologic Features Similar to Non-Tuberculous Mycobacteriosis

  • 최선미 (서울대학교 의과대학 내과학교실) ;
  • 강효재 (서울대학교 의과대학 내과학교실) ;
  • 정윤정 (서울대학교 의과대학 내과학교실) ;
  • 임주현 (서울대학교 의과대학 내과학교실) ;
  • 최원석 (서울대학교 의과대학 내과학교실) ;
  • 황상현 (국립암센터 진단검사의학과) ;
  • 박진경 (국립암센터 폐암센터) ;
  • 황보빈 (국립암센터 폐암센터) ;
  • 이희석 (국립암센터 폐암센터)
  • Choi, Sun-Mi (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Kang, Hyo-Jae (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Jeong, Yun-Jeong (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Lim, Joo-Hyun (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Choe, Won-Seok (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Hwang, Sang-Hyun (Department of Laboratory Medicine, National Cancer Center) ;
  • Park, Jin-Kyeong (Center for Lung Cancer, National Cancer Center) ;
  • HwangBo, Bin (Center for Lung Cancer, National Cancer Center) ;
  • Lee, Hee-Seok (Center for Lung Cancer, National Cancer Center)
  • 투고 : 2011.08.29
  • 심사 : 2011.09.16
  • 발행 : 2012.01.30

초록

In 2005, a group of mycolic acid-containing bacteria was characterized as belonging to a novel genus, Segniliparus with species Segniliparus rugosus and S. rotundus. We report a case of the S. rugosus isolated from a 54-year-old woman with radiologic features mimicking that of non-tuberculous mycobacteriosis (NTM). When the patient first visited our hospital, an acid-fast bacteria (AFB) smear tested positive and Mycobacterium tuberculosis polymerase chain reaction (TB PCR) was negative in the bronchoalveolar lavage sample. After 2 months, the growing colonies were reported as NTM, but could not be identified because they had died. One year after the initial visit, induced sputum samples showed the same results, positive AFB smear and negative TB PCR. At this point, the growing colonies were identified as S. rugosus. Therefore, we should consider Segniliparus genus as a differential diagnosis for AFB in respiratory specimens in addition to the genus Mycobacterium.

키워드

참고문헌

  1. Butler WR, Floyd MM, Brown JM, Toney SR, Daneshvar MI, Cooksey RC, et al. Novel mycolic acid-containing bacteria in the family Segniliparaceae fam. nov., including the genus Segniliparus gen. nov., with descriptions of Segniliparus rotundus sp. nov. and Segniliparus rugosus sp. nov. Int J Syst Evol Microbiol 2005;55: 1615-24.
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