Biomedical Science Letters (대한의생명과학회지)

The Korean Society for Biomedical Laboratory Sciences (대한의생명과학회)
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A Correlation between Urinary Methylhippuric Acid and Hematologic Finding and Urinalysis Index due to Xylene Exposure

  • Lee, Won-Gun (Department of Biomedical Laboratory Science, School of Medicine, Eulji University) ;
  • Kim, In-Sik (Department of Biomedical Laboratory Science, School of Medicine, Eulji University) ;
  • Kang, Sang-Sun (Department of Biology Education, Chungbuk National University) ;
  • Hyun, Sung-Hee (Department of Biomedical Laboratory Science, School of Medicine, Eulji University)
  • Received : 2011.12.19
  • Accepted : 2012.03.30
  • Published : 2012.03.31
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Abstract

This study was performed to investigate the urinary methyl hippuric acid (UMHA) excretion among aircraft maintenance workers exposed to xylene by examination of blood test, urine test and biochemical tests. Study subjects (301) were divided into 2 groups; non-exposed group (n=123, who were not exposed to xylene), and exposed group (n=178, who were exposed to xylene). The average of blood level and MHA level was normal. The ${\gamma}$-GTP level was 35.5 IU/L (45.7%) in the exposed group and 27.9 IU/L (44.7%) in the non-exposed (control) group. The proportion of total cholesterol (TG) level higher than 150 mg/dl were 34.3% in the exposed group and 21.1% in the non-exposed group. These results were showed statistically significant difference (${\chi}^2$ = 6.10, P<0.05). Other items showed no statistically significant differences. The results of urine tests were no statistically significant differences in protein, occult blood and glucose level.

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