초록
For the solution of necessary artificial blood and its substitutes to human being, recent advances on the development of artificial blood have been reviewed from the analysis of literatures published during 26 years from 1986 to 2011. The trends of investigative development for artificial blood, the statistical analysis of the papers published on blood substitutes, and the national distribution of the papers published on artificial blood have been also summarized and discussed precisely. The approach for the application of the stem cell technology to produce the artificial blood has been suggested on the basis of the experienced knowledges of several individual institutions on the world. The perspectives of new methods to produce the artificial blood and its substitutes are bring to be expected and pointed out from the stem cell nanobiotechnology in near future.