Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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An Anacardic acid Analog from the Jellyfish-derived Fungus Paecilomyces variotii

  • Liu, Juan (College of Pharmacy, Pusan National University) ;
  • Li, Famei (Shenyang Pharmaceutical University) ;
  • Lee, Yoon-Mi (College of Pharmacy, Pusan National University) ;
  • Li, Jian Lin (College of Pharmacy, Pusan National University) ;
  • Hong, Jong-Ki (College of Pharmacy, Kyung Hee University) ;
  • Yoon, Won-Duk (National Fisheries Research & Development Institute) ;
  • Kim, Eui-Kyung (College of Veterinary Medicine, Gyeongsang National University) ;
  • Jung, Jee-H. (College of Pharmacy, Pusan National University)
  • Received : 2011.12.19
  • Accepted : 2012.01.20
  • Published : 2012.03.31
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Abstract

An anacardic acid analog (1) was isolated from the fungus Paecilomyces variotii which was derived from the giant jellyfish Nemopilema nomurai. Compound 1 was isolated from a natural source for the first time and was evaluated for antibacterial activity against human and marine pathogens, including MDR (multidrugresistant) strains. Compound 1 exhibited mild antibacterial activity against Escherichia coli DC 2, Streptococcus iniae, and methicillin-resistant Staphylococcus aureus 3089 (MRSA).

Keywords

References

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