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Korean Carbon Society (한국탄소학회)
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Temperature and pH-Responsive Release Behavior of PVA/PAAc/PNIPAAm/MWCNTs Nanocomposite Hydrogels

  • Jung, Gowun (Department of Fine Chemical Engineering and Applied Chemistry, BK21-E2M, Chungnam National University) ;
  • Yun, Jumi (Department of Fine Chemical Engineering and Applied Chemistry, BK21-E2M, Chungnam National University) ;
  • Kim, Hyung-Il (Department of Fine Chemical Engineering and Applied Chemistry, BK21-E2M, Chungnam National University)
  • Received : 2012.05.25
  • Accepted : 2012.06.16
  • Published : 2012.07.31
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Abstract

A drug delivery system (DDS) was prepared with a temperature and pH-responsive hydrogel. Poly(vinyl alcohol) (PVA)/poly(acrylic acid) (PAAc)/poly(N-isopropylacrylamide) (PNIPAAm)/multi-walled carbon nanotube (MWCNT) nanocomposites were prepared by radical polymerization for the temperature and pH-responsive hydrogels. MWCNTs were employed to improve both the thermal conductivity and mechanical properties of the PVA/PAAc/PNIPAAm/MWCNT nanocomposite hydrogels. Various amounts of MWCNTs (0, 0.5, 1 and 3 wt%) were added to the nanocomposite hydrogels. PVA/PAAc/PNIPAAm/MWCNT nanocomposite hydrogels were characterized with a scanning electron microscope. The mechanical properties were measured with a universal testing machine. Swelling and releasing properties of nanocomposite hydrogels were investigated at various temperatures and pHs. Temperature and pH-responsive release behavior was found to be dependent on the content of MWCNTs in nanocomposite hydrogels.

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References

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