Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Effects of Aerobic Exercise and a Protein Diet on Serum Lipid Profiles, Liver Function, and Immunoglobulin in Rats

유산소 운동과 단백식이가 흰쥐의 혈중지질, 간기능 및 면역글로불린에 미치는 영향

  • Sung, Gi-Dong (Department of Physical Education, Pusan National University) ;
  • Son, Won-Mok (Department of Physical Education, Pusan National University) ;
  • Baek, Yeong-Ho (Department of Physical Education, Pusan National University)
  • 성기동 (부산대학교 체육교육학과) ;
  • 손원목 (부산대학교 체육교육학과) ;
  • 백영호 (부산대학교 체육교육학과)
  • Received : 2011.11.16
  • Accepted : 2012.01.13
  • Published : 2012.01.30
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Abstract

The purpose of this study was to analyze the effects of aerobic exercise and a protein diet on serum lipid profiles, liver function, and immunoglobulin levels in rats. The subjects, 24 male Sprague-Dawley rats, were grouped into an exercise with protein diet group (A, n=6), a protein diet group (B, n=6), an exercise group (C, n=6), and a control group (D, n=6). The exercise with protein group trained for 4 weeks (20-30 min/day, speed at 14~17 m/min) and was given a 40% protein diet for 4 weeks. The variables of serum lipid profiles, liver function, and immunoglobulin levels were measured in all of the subjects at the end of the 4 weeks of treadmill exercise. Serum TC and LDL-C levels were significantly decreased in the exercise with protein diet group compared to the other groups and serum HDL-C, GOP, and IgG were significantly higher than in the other groups. However, no significant differences were found for the IgA and IgM levels. In conclusion, aerobic exercise with a protein diet was effective in improving serum lipid profiles, liver function, and immunoglobulin.

본 연구는 4주간의 유산소운동과 단백질 섭취가 흰쥐의 혈중지질, 간기능 및 면역글로불린에 미치는 영향을 구명하기 위하여 실시하였다. 실험동물은 총 24마리를 대상으로 4주간 20-30분씩 14~17 m/min의 속도로 트레드밀을 이용하여 유산소 운동을 실시하였으며, 운동단백식이군(A, n=6), 단백식이군(B, n=6), 운동군(C, n=6), 대조군(D, n=6)으로 분류하였고, 유산소 운동 4주후 혈중지질, 간기능 및 면역글로불린 농도를 측청하여 비교 분석하였다. 본 연구 결과 유산소 운동과 단백질식이를 실시 후 총콜레스테롤(TC)는 운동단백식이군이 유의하게 낮은 것으로 나타났으며, 중성지방(TG)는 운동군이 유의하게 낮았다. 고밀도지단백 콜레스테롤(HDL-C)는 운동단백식이군이 유의하게 높았으며, 저밀도지단백 콜레스테롤(LDL-C)는 운동단백식이군과 운동군이 유의하게 낮게 나타났다. 간기능에서는 운동단백식이군과 단백식이군이 유의하게 높았으며, GPT는 차이가 없었다. 면역글로불린 IgG는 운동단백식이군이 대조군보다 유의하게 높았나, IgA, IgM은 차이가 없었다. 따라서 유산소 운동과 단백섭취는 혈중지질 개선과 간기능 및 면역글로불린 IgG에 긍정적인 영향을 미쳐 심혈관 질환을 예방하고 항체 형성 인자에 영향을 주어 인체의 면역항체 형성에 효과가 있을 것으로 사료된다.

Keywords

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