The Korean Journal of Medicine

  • 제82권4호
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  • Pages.403-410
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  • 2012
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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갈색세포종의 진단과 치료

Diagnosis and Treatment of Pheochromocytoma

  • 유순집 (가톨릭대학교 의과대학 부천성모병원 내분비내과)
  • Yoo, Soon-Jib (Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Bucheon St. Mary's Hospital)
  • 발행 : 2012.04.01
⟨ 이전 논문 다음 논문 ⟩

초록

Pheochromocytomas are rare neuroendocrine tumours with a highly variable and heterogeneous clinical manifestation. With a noticeable progress in genetics, biochemical diagnosis and tumour imaging techniques, modifications of the traditional "rule of tens" for pheochromocytomas are inevitable consequence. Diagnosis of pheochromocytoma depends on biochemical evidence of catecholamine production by the tumor. Plasma free metanephrines provide the best test for excluding or confirming pheochromocytoma and should be used as an initial screening tool, but if it is not available, urinary fractionated metanephrines could be used as an alternative method. Different anatomical and functional imaging modalities are used to localize biochemically proven pheochromocytomas. These include computed tomography, magnetic resonance imaging, single-photon emission computed tomography (SPECT) using $^{123/131}I$-metaiodobenzylguanidine (MIBG) or $^{111}In$-DTPA-pentetreotide and positron emission tomography (PET). Timely laparoscopic tumour removal in combination with appropriate pre-and intraoperative management of the effects of secreted catecholamines are essential components for excellent prognosis.

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참고문헌

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피인용 문헌

  1. Characterization of Incidentally Detected Adrenal Pheochromocytoma vol.27, pp.2, 2012, https://doi.org/10.3803/enm.2012.27.2.116
  2. A Case of Pheochromocytoma Misdiagnosed as Activation of Behcet's Disease vol.85, pp.3, 2013, https://doi.org/10.3904/kjm.2013.85.3.334
  3. A Case of Pheochromocytoma Associated with Diabetic Ketoacidosis and Infective Endocarditis vol.14, pp.3, 2013, https://doi.org/10.4093/jkd.2013.14.3.156
  4. A Case of Pheochromocytoma Presenting as Ventricular Tachycardia Storm vol.89, pp.2, 2012, https://doi.org/10.3904/kjm.2015.89.2.215
  5. Acute Aortic Dissection in a Patient with Pheochromocytoma vol.92, pp.3, 2012, https://doi.org/10.3904/kjm.2017.92.3.286
  6. Diabetes and Endocrine Disease vol.18, pp.3, 2012, https://doi.org/10.4093/jkd.2017.18.3.155
  7. 척추와 대동맥주위 림프절로 전이한 거대 갈색세포종 vol.34, pp.2, 2017, https://doi.org/10.12701/yujm.2017.34.2.247