The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Hepatocellular Carcinoma with Progressive Metastasis to the Oral Cavity

구강내 전이로 진행한 전이성 간세포암 1예

  • Kim, Tae-Hun (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Jeon, Gi-Jung (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Ma, Bong-Oh (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Yang, Hae-Jin (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Lee, Jae-Un (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Yoon, Seong-Min (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine)
  • 김태훈 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 전기정 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 마봉오 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 양혜진 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 이제운 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 윤성민 (성균관대학교 의과대학 삼성창원병원 내과)
  • Published : 2012.08.01
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Abstract

Hepatocellular carcinoma (HCC) usually metastasizes to the lung, breast, lymph nodes, gastrointestinal tract, bone, kidney, and/or adrenal gland. Metastasis of HCC to the hard palate and tonsils is a rare phenomenon. Thus, we report a case of HCC with metastasis to the hard palate and both tonsils in a 45-year-old man. The patient was admitted to our hospital with a complaint of oral bleeding. Physical examination revealed a bleeding tumor located in the hard palate and histological examination showed metastasis from HCC. The patient died 2 months later due to multiple organ failure, although bleeding was controlled by radiotherapy.

본 증례는 간세포암으로 진단받고 경동맥 색전술을 5차례 받았으나 추적관찰 중 5개월 후에 폐, 림프절, 뼈 등 여러 장기로 전이되었고, 이후 2개월이 지나 경구개와 양쪽 편도에서 모두 종양이 생겨 구강 출혈을 주소로 내원하였다. 실시한 조직 검사에서 경구개와 편도에서 전이소견을 보였으며, 방사선 치료로 더 이상 출혈은 없었으나 60일 후 다발성 장기부전으로 사망한 증례를 경험하여 문헌고찰과 함께 보고한다.

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References

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