The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Effects of Hovenia dulcis Thunberg Extract on Enzymes Related Reactive Oxygen Intermediate

헛개나무(Hovenia dulcis Thunberg) 추출물이 활성 산소종과 관련한 효소에 미치는 영향

  • 김은호 (국립과학수사연구원 법과학부 화학분석과) ;
  • 이광수 (장안대학교 건강과학부 식품영양과)
  • Received : 2012.11.20
  • Accepted : 2012.12.07
  • Published : 2012.12.31
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Abstract

In order to investigate the effects of 70% EtOH extract obtained from Hovenia dulcis Thunberg on enzymes relating reactive oxygen intermediate, cancer-stricken animals induced by DEN (N,N-diethylnitrosamine) were recovered by administering the extract of Hovenia dulcis Thunberg. It showed that there was no effect on the generation of superoxide radical by the extract of Hovenia dulcis Thunberg. However, considering the increase of the activity of Cu, Zn-SOD and Mn-SOD in the tested animal class, the extract of Hovenia dulcis Thunberg could participate directly in removing of superoxides. The experimented-animals treated with the extract of Hovenia dulcis Thunberg showed an increase in the activity of the enzymes, catalase and glutathione peroxidase, which can eliminate hydrogen peroxide pertained in liver tissue. The extract of Hovenia dulcis Thunberg seemed to have some factors that accelerate the oxidation. Also, the extract of Hovenia dulcis Thunberg showed effects on the enzymes relating to the active oxygen toxicity which could be an indicator of aging and body toxicity.

Keywords

References

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