The Effect of Acupuncture and Electro-acupuncture at ST41 on Experimentally-induced Intestinal Hypo-motility in Rats: Comparison between Pre-treatment and Post-treatment

해계(解谿)(ST41) 유침 및 전침의 전.후처치가 loperamide로 억제된 흰쥐의 장운동에 미치는 영향

  • Kim, KyungMin (Dept. of Meridians & Acupoints, College of Oriental Medicine, Daejeon University) ;
  • Lee, Hyun (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Yim, YunKyoung (Dept. of Meridians & Acupoints, College of Oriental Medicine, Daejeon University)
  • 김경민 (대전대학교 한의과대학 경락경혈학교실) ;
  • 이현 (대전대학교 한의과대학 침구학교실) ;
  • 임윤경 (대전대학교 한의과대학 경락경혈학교실)
  • Received : 2012.04.05
  • Accepted : 2012.07.13
  • Published : 2012.09.30

Abstract

Objectives: The purpose of this study was to investigate the effect of acupuncture and electro-acupuncture (EA) of low and high frequencies at Haegye (ST41) in rats. Methods: The intestinal motility of rats was experimentally suppressed with loperamide. Acupuncture, low frequency EA and high frequency EA were carried out before the loperamide administration in the pre-treatment group, and after the loperamide administration in the post-treatment group. The rats were fed charcoal and the travel rate of charcoal in the gastrointestinal track was measured to analyze the effect of acupuncture, low frequency EA and high frequency EA on the intestinal hypo-motility. Results: 1. None of acupuncture, low frequency EA or high frequency EA at ST41 showed significant influences on intestinal motility of rats in normal status. 2. Pre-treatment with acupuncture at ST41 showed no significant effect on the intestinal hypo-motility induced by loperamide in rats. 3. Pre-treatment with low frequency EA and high frequency EA at ST41 significantly reduced the suppression of intestinal motility by loperamide in rats. 4. Post-treatment of acupuncture, low frequency EA and high frequency EA at ST41 had no significant influences on the intestinal hypo-motility induced by loperamide in rats. Conclusions: These results suggest that low and high frequency EA at ST41 may be effective to prevent gastric disorders such as intestinal hypo-motility.

Keywords

References

  1. 대한내과학회 편집위원회. 해리슨내과학. 서울:도서출판 MIP. 2006:1863-967.
  2. 홍원식. 정교황제내경영추. 서울:동양의학연구원출판부. 1981:21,39,123,176.
  3. 김달호. 황제내경소문. 서울:의성당. 2001:158-65, 192.
  4. 전국한의과대학 침구경혈학교실 편저. 침구학(下). 서울:집문당. 2004:1017-20, 1447-51.
  5. 楊繼洲. 鍼灸大成. 台北:文光圖書有限公司.1989:112-314.
  6. Lee SH, Yim YK, Lee H. The Effect of Acupuncture and Electro-acupunture Of Low and High Frequencies at SP6 on Experimentally Induced Intestinal Hypermotility in Rats: Comparison Between Pre-treatment and Post-treatment. Dept. of Acupuncture& Moxibustion, College of Oriental Medicine, Daejeon Universiry. 2008;25(4):105-16.
  7. Nam SH, Lee H. Effect of Pre-treatment or Post-treatmant of Acupuncture Low Frequency Electro-acupuncture and High Frequency Electro-acupuncture at LI4 on Intestinal Motility in Rats: Dept. of Acupuncture& Moxibustion. College of Oriental Medicine, Daejeon Universiry. 2009;27(3):117-26, 2008;25(4):11-29.
  8. Lee EK, Choi EH, Jeon JH, Kim YI. Effect of Acupuncture and High Frequency Electro-acupunture at ST39 on Intestinal Motility in Rats. Dept. of Acupuncture& Moxibustion, College of Oriental Medicine, Daejeon Universiry. 2009; 26(2):79-89.
  9. Lim SC, Lee H. Effect of Acupuncture and Electro-acupunture at LR3 on Intestinal Motility in Rats. Dept. of Acupuncture& Moxibustion, College of Oriental Medicine, Daejeon Universiry. 2008;25(5):27-42.
  10. Choi JY, Lee H. The Effect of Acupuncture and Electro-acupunture Of Low and High Frequencies at ST41 on Experimentally Induced Intestinal Hypermotility in Rats: Comparison Between Pre-treatment and Post-treatment. Dept. of Acupuncture& Moxibustion, College of Oriental Medicine, Daejeon Universiry. 2009; 27(3):117-126.
  11. Available at: URL: http://www.spss.co.kr
  12. Choo KY, Choi MG, Choi KW. The prevalences of gastrointestinal symptoms in a rural community in Korea. Kor J of Neurogastroenterol Motil. 2000;6:31-43
  13. 전국한의과대학 비계내과학교수 공저. 비계내과학. 서울:한성기획. 2000:7-11.
  14. Authur CG, John EH. Medical Physiology. Seoul:JungDam. 2002:830-46.
  15. 이윤호. 침자수법. 서울:정담. 1996:147-51.
  16. 조민수, 안창범. 자침의 제반 수기법과 보사법에 대한 고찰. 대한침구학회지. 1993;10(1):61-74.
  17. Kim JG. Electro-treatment of Theory and Clinical research. Seoul:Suwundang. 1993:14-17.
  18. 한국약학대학협의회 약물학분과회. 약물학. 서울:신일상사. 2004:536.
  19. Charles FL, Lora LA, Morton PG, Leonard LL. drug information handbook. LEXI-COMP. 2006:265, 949-951.
  20. Teodorou V, Fioramonti J, Hacher T, Bueno L. Absorptive and mortor components of the antidiarrhoeal action of Loperamide : An invivo study in pigs. Gut. 1983;32:1355-93.