Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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The effect of Baeckji, Seasin, Baeckgangjam and Myunkanbang on skin-whitening

백지, 세신, 백강잠 및 면간방이 피부미백에 미치는 영향

  • Jeon, Sang-Hun (Department of Beauty & Medicine, Graduate School of Public Health and Sports) ;
  • Lim, Mi-Hye (Department of Beauty & Medicine, Graduate School of Public Health and Sports)
  • 전상훈 (대전대학교 보건스포츠대학원 미용의학과) ;
  • 임미혜 (대전대학교 보건스포츠대학원 미용의학과)
  • Received : 2011.04.10
  • Accepted : 2011.04.23
  • Published : 2011.06.30
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Abstract

To develope new natural substances for whitening agent, Baeckji(Angelica dahuria;BK), Seasin(Asarum sieboldii;SS). Baecjgangjam(Bombycis corpus;BGJ) and Mynkanbang(MKB) were selected and extracted by hot water and 70% EtOH, respectively. Hydrothermal and ethanolic extracts of BK, SS, BGJ and MKB were evaluated for anti-oxidative effect, tyrosinase activity, melanogenesis of B16 melanoma cells and changes in level of tyrosinase expression by using Western blotting. All hydrothermal and ethanolic extracts showed scavenging activities of free radicals against 1,1-diphenyl-2-picrylhydrazyl(DPPH) but no inhibitory effect on tyrosinase activity. Ethanolic extracts of BK, SS, and BGJ and especially highly, those of MKB inhibited production of melanin in B16 melanoma cells and were able to reduce the level of tyrosinase expression in B16 melanoma cells. These results suggest that ethanolic extracts of BK, SS, BGJ and MKB can be an effective whitening agent from natural plant.

Keywords

References

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