핵의학기술 (The Korean Journal of Nuclear Medicine Technology)
- 제15권1호
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- Pages.34-38
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- 2011
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- 1229-9901(pISSN)
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- 2982-8406(eISSN)
장비에 따른 SUV의 차이와 이에 관한 고찰
Assessment and Comparison of SUVs of Three Different PET/CT Scanners
- 김태엽 (서울특별시립 보라매병원 핵의학과) ;
- 임정진 (서울특별시립 보라매병원 핵의학과) ;
- 이홍재 (서울대학교병원 핵의학과) ;
- 김현주 (서울대학교병원 핵의학과) ;
- 김중현 (서울대학교 핵의학교실) ;
- 이재성 (서울대학교병원 핵의학과)
- Kim, Tae-Yeob (Department of Nuclear Medicine, SMG-SNU Boramae Medical Center) ;
- Lim, Jung-Jin (Department of Nuclear Medicine, SMG-SNU Boramae Medical Center) ;
- Lee, Hong-Jae (Department of Nuclear Medicin, Seoul National University Hospital) ;
- Kim, Hyun-Joo (Department of Nuclear Medicin, Seoul National University Hospital) ;
- Kim, Joong-Hyun (Department of Nuclear Medicine, Seoul National University) ;
- Lee, Jae-Sung (Department of Nuclear Medicin, Seoul National University Hospital)
- 투고 : 2010.12.28
- 심사 : 2011.03.07
- 발행 : 2011.04.30
초록
표준섭취계수(Standard Uptake Value, SUV)는 PET 검사에 있어서 매우 중요한 지표이다. 그러나 이는 장비에 따라서 다르게 나타난다. 그러므로 실제의 SUV와 장비에 따른 SUV의 차이를 알아보고자 한다. 실험을 위해 사용된 PET scanner는 본원과 보라매 병원에서 사용하고 있는 Biograph True Point True V 40 (Siemens, USA), Gemini Dual (Philips, USA), Gemini TF 64 (Philips, USA) 총 3대로 이루어져 있다. SUV를 평가하기 위한 phantom은 NEMA PET phantom (Data Spectrum co., USA)이고 내부에 3개의 hot insert를 포함하고 있으며 총 중량은 6.8kg으로 phantom과 물의 중량을 합친 무게이다. 방사성동위원소는
Purpose: The SUV is a widely used semi-quantitative index in PET for the estimation of radio-tracer accumulation in VOI. In this study, SUVs from three different PET/CT scanners were assessed, and differences between SUVs were evaluated. Materials and Methods: The PET/CT scanners which were assessed in this study were GEMINI, GEMINI TF 64 (Philips) and Biograph True Point True V 40 (Siemens). The NEMA PET phantom (Data Spectrum Corp., USA) was used to evaluate SUVs. The NEMA PET phantom has6.8 kg weight and three hot inserts. Two different activity distributions for the background and inserts were tested. The activity ratio were 3.7:3.7:7.4:11.1 MBq (1:1:2:3) and 1.85:7.4:9.25:11.1MBq (1:4:5:6) for each of background, insert 1, insert 2 and insert 3. Acquisition time was 2 minutes per bed position and NEMA PET phantom could be covered by two bed positions for all PET/CT scanners. The SUVs from each PET/CT scanner were compared with calculated true value. Results: For both activity ratios, all scanners showed similar results. The differences between each scanner were insignificant. Each scanner showed 91.2%, 85.9% and 87.2% of true SUV for GEMINI, GEMINI TF 64, Biograph True Point TrueV, respectively. Conclusion: For all scanners, SUVs were slightly lower than true value. However, the difference between scanners was insignificant. The SUVs from these scanners would be clinically meaningful if their consistent underestimation is kept in mind.