Journal of Nutrition and Health

  • 제44권2호
  • /
  • Pages.112-118
  • /
  • 2011
  • /
  • 2288-3886(pISSN)
  • /
  • 2288-3959(eISSN)
한국영양학회 (The Korean Nutrition Society)
권호 표지
DOI QR코드

DOI QR Code

우리나라 일부 영아의 혈액 셀레늄과 Glutathione Peroxidase 효소 활성에 관한 연구

Selenium Status and Glutathione Peroxidase Activity in Korean Infants

  • 김현하 (용인대학교 식품영양학과) ;
  • 양혜란 (분당서울대학교병원 소아청소년과) ;
  • 김혜영 (용인대학교 식품영양학과)
  • Kim, Hyun-Ha (Department of Food and Nutrition, Yongin University) ;
  • Yang, Hye-Ran (Department of Pediatrics, Seoul National University Bundang Hospital) ;
  • Kim, Hye-Young (Department of Food and Nutrition, Yongin University)
  • 투고 : 2011.01.28
  • 심사 : 2011.03.23
  • 발행 : 2011.04.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

We investigated the selenium (Se) nutrition status in Korean infants. The mean serum Se concentration in infants was 66.9 ${\mu}g/L$, and it increased with increasing in infant age: 57.6 ${\mu}g/L$ at 0-5 months, 71.8 ${\mu}g/L$ at 6-11 months, and 75.5 ${\mu}g/L$ at 12-24 months. Serum glutathione peroxidase (GPx) activity also increased with infant age. Serum Se concentration in infants was positively correlated with serum GPx activity (r = 0.565, p < 0.01). At 0-5 months, human milk-fed infants tended to have higher Se concentrations and GPx activity than those of formula-fed infants, but the result was not significant. With the introduction of supplemental feeding at 6-24 months of age, serum Se concentration was not different between the groups. Therefore, human milk feeding seemed to be more appropriate for infant Se nutrition than infant formula feeding during the first 6 months of life, but supplemental feeding became more important later to maintain good Se nutrition status.

키워드

참고문헌

  1. Rayman MP. The importance of selenium to human health. Lancet 2002; 356: 233-241
  2. Berry MJ, Banu L, Larsen PR. Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature 1991; 349: 438-440 https://doi.org/10.1038/349438a0
  3. Burk RF. Recent developments in trace elements metabolism and function: newer roles of selenium in nutrition. J Nutr 1989; 119: 1051-1054
  4. Sunde RA. Molecular biology of selenoproteins. Annu Rev Nutr 1990; 10: 451-474 https://doi.org/10.1146/annurev.nu.10.070190.002315
  5. Kim HYP. Recent food and nutrition information: Selenium. National Nutr 1997; 192: 14-20
  6. Kim HYP. Children's disease related with selenium deficiency. Bull Yongin Univ 1995; 11: 405-425
  7. Levander OA, Burk RF. Report on the 1986 ASPEN Research Workshop on selenium in clinical nutrition. J Parenter Enteral Nutr 1986; 10(6): 545-549 https://doi.org/10.1177/0148607186010006545
  8. Rayman MP. Selenium in cancer prevention: a review of the evidence and mechanism of action. Proc Nutr Soc 2005; 64(4): 527-542 https://doi.org/10.1079/PNS2005467
  9. Choi YS, Hesketh JE. Nutritional biochemistry of selenium. J Korean Soc Food Sci Nutr 2006; 35(5): 651-660
  10. Lombeck I, Kasperek K, Harbisch HD, Feinendegen LE, Bremer HJ. The selenium state of healthy children. I. Serum selenium concentration at different ages; activity of glutathione peroxidase of erythrocytes at different ages; selenium content of food of infants. Eur J Pediatr 1977; 125(1): 81-88 https://doi.org/10.1007/BF00470608
  11. The Korean Nutrition Society. Dietary reference intakes for Koreans. 1st revision. Seoul; 2010
  12. Rotruck JT, Pope A, Ganther ME, Swanson AB, Hafeman DG, Hoekstra WG. Selenium: Biochemical role as a component of glutathione peroxidase. Science 1973; 179: 588-590 https://doi.org/10.1126/science.179.4073.588
  13. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids. Washington DC; 2000
  14. Ro HK. Factors to affect changes in feeding method of infants. In: Pregnancy, Lactation and Infant's Nutrition. Seoul: Kyo- Moon Sa ; 2000. p.9-26
  15. Ministry of Health and Welfare, Korea Center for Disease Control and Prevention. 2008 National health and nutrition examination survey report. Seoul; 2009
  16. Dorea JG. Selenium and breast-feeding. Br J Nutr 2002; 88(5): 443-461 https://doi.org/10.1079/BJN2002692
  17. Moon SJ, Kang JS, Lee MJ, Lee JH, Ahn HS. A longitudinal study of micro-mineral concentrations in human milk. Korean J Nutr 1995; 28(7): 620-628
  18. Yang HR, Keum HK, Kim ES. A study on the contents of selenium and zinc in human milk. Korean J Nutr 1995; 28(9): 872-879
  19. Kim HYP. Selenium concentration in human milk and selenium nutrition status of infants. In: Pregnancy, Lactation and Infant's Nutrition. Seoul: Kyo-Moon Sa ; 2000. p.185-200
  20. KFDA. Report of the scientific committee on the revision of essential requirements of infant formulae and follow-on formula. Seoul; 2007
  21. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158-169
  22. Korean Pediatric Society. Physical growth of children in Korea; 2007
  23. Muntau AC, Streiter M, Kappler M, Roschinger W, Schmid I, Rehnert A, Schramel P, Roscher AA. Age-related reference values for serum selenium concentrations in infants and children. Clin Chem 2002; 48(3): 555-560
  24. Locktch G, Halstead AC, Wadsworth L, Quigley G, Reston L, Jacobson B. Age- and sex-specific pediatric reference intervals and correlations for zinc, copper, selenium, iron, vitamins A and E, and related proteins. Clin Chem 1988; 34(8): 1625-1628
  25. Smith AM, Chen LW, Thomas MR. Selenate fortification improves selenium status of term infants fed soy formula. Am J Clin Nutr 1995; 61(1): 44-47
  26. Litov RE, Comb SGP. Selenium in pediatric nutrition. Pediatr 1991; 87(3): 339-351
  27. Hill KE, Xia Y, Akesson B, Boeglin ME, Burk RF. Selenoprotein P concentration in plasma is an index of selenium status in selenium-deficient and selenim-supplemented Chinese subjects. J Nutr 1996; 126: 138-145. https://doi.org/10.1093/jn/126.1.138
  28. Xia Y, Hill KE, Bryne DW, Xu J, Burk RF. Effectiveness of selenium selenium supplements in a low-selenium area of China. Am J Clin Nutr 2005; 81: 829-834
  29. Verlinden M, Van Sprundel M, Van der Auwera JC, Eylenbosch WJ. The selenium status of Belgian population groups. II. Newborns, children, and the aged. Biol Trace Elem Res 1983; 5: 103-113 https://doi.org/10.1007/BF02916630
  30. Bro S, Berendtsen H, Norgaard J, Hose A, Jorgensen PJ. Serum selenium concentration in maternal and umbilical cord blood. Relation to course and outcome of pregnancy. J Trace Elem Electrolytes Health Dis 1988; 2: 165-169
  31. Shen L, Van Dael P, Luten J, Deelstra H. Geographic distribution of selenium bioavailability from human, cow's, goat and sheep milk by an in vitro method. Int J Food Sci and Nutr 1996; 47: 75-81 https://doi.org/10.3109/09637489609028564
  32. Kumpulainen J, Salmenpera L, Siimes MA, Koivistoinen P, Lehto J, Perheentupa J. Formula feeding results in lower selenium status than breast-feeding or selenium supplemented formula feeding: a longitudinal study. Am J Clin Nutr 1987; 45: 49-53
  33. Hatano S, Aihara K, Nishi Y, Usui T. Trace elements in plasma and erythrocytes in relation to dietary intake during infancy. J Pediatr Gastroenterol Nutr 1985; 4: 87-92 https://doi.org/10.1097/00005176-198502000-00016
  34. Rossipal E, Tiran B. Selenium and glutathione peroxidase levels in healthy infants and children in Austria and the influence of nutrition regimens on these levels. Nutrition 1995; 11(S5): S573-S575.
  35. Millar KR, Sheppard AD. -tocopherol and selenium levels in human and cows' milk. New Zealand J Sci 1972; 15: 3-15
  36. Smith AM, Picciano MF, Milner JA. Selenium intakes and selenium status of human milk and formula-fed infants. Am J Clin Nutr 1982; 35: 521-526
  37. Smith AM, Chan GM, Moyer-Mileur LJ, Johnson CE, Gardner BR. Selenium status of preterm infants fed human milk, preterm formula, or selenium-supplemented preterm formula. J Pediatr 1991; 119: 429-433 https://doi.org/10.1016/S0022-3476(05)82058-X
  38. McGuire MK, Burgert SL, Milner JA, Glass L, Kummer R, Deering R, Boucek R, Picciano MF. Selenium status of infants is influenced by supplementation of formula or maternal diets. Am J Clin Nutr 1993; 58(5): 643-648
  39. Jochum F, Fuchs A, Menzel H, Lombeck I. Selenium in German infants fed breast milk or different formulas. Acta Paediatrica 1995; 84(8): 859-862 https://doi.org/10.1111/j.1651-2227.1995.tb13780.x
  40. Daniels L, Gibson R, Simmer K. Selenium status of preterm infants: The effect of postnatal age and method of feeding. Acta Paediatrica 1997; 86: 281-288 https://doi.org/10.1111/j.1651-2227.1997.tb08891.x
  41. Friel JK, Andrews WL, Edgecome C, McCloy UR, Belkhode SL, L'Abbe MR, Mercer CN, McDonald AC. Eighteen-month follow- up of infants fed evaporated milk formula. Can J Pub Health 1999; 90: 240-243
  42. Sievers E, Arpe T, Schleyerbach U, Garbe-Schonberg D, Schaub J. Plasma selenium in preterm and term infants during the first 12 months of life. J Trace Element Med Biol 2001; 14: 218-222 https://doi.org/10.1016/S0946-672X(01)80005-5

피인용 문헌

  1. Determination of selenium in grains by hydride generation-ICP/MS vol.26, pp.2, 2013, https://doi.org/10.5806/AST.2013.26.2.135
  2. Analysis of selenoaminoacids and selenoproteins in blood serum of sows fed by selenium fortified feed vol.28, pp.3, 2015, https://doi.org/10.5806/AST.2015.28.3.196
  3. Nutrient Intakes and Hair Mineral Contents of Young Children vol.19, pp.2, 2016, https://doi.org/10.5223/pghn.2016.19.2.123
  4. 셀레늄이 전리방사선에 의한 힌쥐 모델에서의 갑상선 항산화계에 미치는 영향 vol.40, pp.1, 2017, https://doi.org/10.17946/jrst.2017.40.1.19