Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Biological Activities of the Water Extract and its Fractions from Taraxacum coreanum Nakai

흰민들레 열수 추출물 및 분획물의 피부 관련 생리활성

  • Lee, Kyoung-In (Biotechnology Industrialization Center, Dongshin University) ;
  • Im, Do-Youn (Dept. of Beauty Science, Kwangju Women's University)
  • 이경인 (동신대학교 생물자원산업화지원센터) ;
  • 임도연 (광주여자대학교 미용과학과)
  • Received : 2011.05.06
  • Accepted : 2011.06.16
  • Published : 2011.06.30
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Abstract

In this study, we investigated on antioxidative activity, tyrosinase inhibitory activity and nitric oxide(NO) production inhibitory activity in the hot water extract of Taraxacum coreanum and its fractions. The total polyphenol and flavonoid contents of the extract were found to be 65.42 mg/g and 9.83 mg/g, respectively. And the total polyphenol and flavonoid contents of the ethyl acetate fraction were found to be 168.23 mg/g and 31.92 mg/g, respectively. In DPPH radical scavenging ability, $SC_{50}$ values of the ethyl acetate and butanol fraction were exhibited 64.65 ${\mu}g/ml$ and 277.42 ${\mu}g/ml$, respectively. Moreover, ethyl acetate fraction showed higher inhibitory activity than other samples in tyrosinase inhibitory activity. In NO production inhibitory activity, the extract and its fractions showed NO production inhibitory effect. Especially, the ethyl acetate, chloroform and butanol fraction was exhibited higher NO production inhibitory activity than other samples. As a result, the ethyl acetate and butanol fraction from the water extract of T. coreanum could be applicable to functional materials for skin-related fields.

Keywords

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