Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Characteristics of L-Ascorbic Acid Encapsulated BGsome and its Stabilization Effect

L-ascorbic acid가 포집된 BGsome의 특성 및 안정화 효과

  • Hwang, Sue-Yun (Department of Applied Chemistry, Dongduk Women's University) ;
  • Jin, Byung-Suk (Department of Applied Chemistry, Dongduk Women's University)
  • 황수연 (동덕여자대학교 자연과학대학 응용화학과) ;
  • 진병석 (동덕여자대학교 자연과학대학 응용화학과)
  • Received : 2011.09.02
  • Accepted : 2011.09.19
  • Published : 2011.09.30
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Abstract

Encapsulation of L-ascorbic acid(AA) into BGsome was attempted to improve its stability. BGsome is a bio-compatible vesicular system prepared by dispersion of hydrated liquid crystalline phase formed through hydration of 1,3-butylene glycol(BG)-dissolved lecithin with an aqueous solution containing hydrophilic component. The characteristics of AA encapsulated BGsome, such as droplet size, surface charge, and solution appearance, was investigated. The concentration of AA solution had considerable effect on droplet size and surface charge of BGsome. Several tens nanometer droplet made by sonication treatment did not showed any change of size with storage time. Stability of AA was improved by encapsulation into BGsome, which was verified through DPPH test and HPLC assay.

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References

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