Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis, Characterization, and Antibacterial Applications of Novel Copolymeric Silver Nanocomposite Hydrogels

  • Kim, Yong-Hyun (Department of Chemistry, Changwon National University) ;
  • Babu, V. Ramesh (Department of Chemistry, Changwon National University) ;
  • Thangadurai, Daniel T. (Department of Chemistry, Changwon National University) ;
  • Rao, K.S.V. krishna (Department of Chemistry, Changwon National University) ;
  • Cha, Hyeong-Rae (Department of Chemistry, Changwon National University) ;
  • Kim, Chang-Dae (Department of Physics, Mokpo National University) ;
  • Joo, Woo-Hong (Department of Biology, Changwon National University) ;
  • Lee, Yong-Ill (Department of Chemistry, Changwon National University)
  • Received : 2010.06.21
  • Accepted : 2010.12.06
  • Published : 2011.02.20
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Abstract

Copolymeric silver nanocomposite hydrogels were synthesized by using acryloyl phenylalanine (APA), N'-isopropylacrylamide (NIPAM) and crosslinked by N,N-methylene bisacrylamide (MBA) via radical redox polymerization. Present study allows entrapping silver nanoparticles into hydrogel networks. UV-visible spectroscopy and X-ray diffraction (XRD) studies confirmed the formation of silver nanoparticles in hydrogel matrix. 11% of weight loss difference between hydrogel and silver nanocomposite hydrogel is clearly indicates the formation and silver nanoparticles by thermo-gravimetrical analysis. The order of swelling capacity values of hydrogels and silver nanocmposite hydrogels were found to be in the order of placebo copolymeric hydrogel >Ag-copolymeric silver nanocomposite hydrogels. The particle size of silver nanoparticles was analysed and are in the range of 5 - 10 nm which has been confirmed by transmission electron microscopy (TEM) as well as particle size analysis. The silver nanocomposite hydrogel has shown very good antibacterial activity on gram-positive and gram-negative bacteriocides.

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