위 침범을 동반한 자가면역성 췌장염

Gastric Involvement in Autoimmune Pancreatitis

  • 백승돈 (울산대학교 의과대학 서울아산병원 소화기내과학교실) ;
  • 김명환 (울산대학교 의과대학 서울아산병원 소화기내과학교실) ;
  • 김윤구 (울산대학교 의과대학 서울아산병원 소화기내과학교실) ;
  • 김도훈 (울산대학교 의과대학 서울아산병원 소화기내과학교실) ;
  • 김지훈 (울산대학교 의과대학 서울아산병원 병리학교실) ;
  • 이상수 (울산대학교 의과대학 서울아산병원 소화기내과학교실) ;
  • 서동완 (울산대학교 의과대학 서울아산병원 소화기내과학교실) ;
  • 이성구 (울산대학교 의과대학 서울아산병원 소화기내과학교실)
  • Baek, Seung-Don (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Myung-Hwan (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Yun-Ku (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Do-Hoon (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Ji-Hun (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sang-Soo (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Seo, Dong-Wan (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sung-Koo (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 발행 : 2011.03.30

초록

자가면역성 췌장염은 비단 췌장 뿐만 아니라 다양한 장기를 침범하는 전신 경화성 질환이다. 자가면역성 췌장염 환자에서 췌장외 장기 침범으로 인하여 위용종이 발생할 수 있으며 떼어 낸 용종에서 면역염색을 하면 IgG4 양성 형질세포의 침윤을 관찰할 수 있다. 본 증례는 자가면역성 췌장염 환자에서 위 용종성 병변이 회오리 모양의 섬유화가 동반되어 IgG4 양성 형질세포 침윤과 연관이 있음을 보여주었다.

Autoimmune pancreatitis is now considered to be a systemic fibroinflammatory disease that can involve multiple organs. As it is associated with IgG4-positive plasma cells by an autoimmune mechanism, extrapancreatic organs as well as the pancreas could be affected with a lymphoplasmacytic infiltrate. The proximal bile duct, the salivary gland, the retroperitoneum and the kidney are well known to be involved with, but less is known about the involvement of hollow viscus which is pathologically associated with autoimmune pancreatitis. We report here on a case of gastric involvement in a 53-year-old man with autoimmune pancreatitis.

키워드

참고문헌

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