Clinical Endoscopy

  • 제41권6호
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  • Pages.390-393
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  • 2010
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  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
권호 표지

상행 결장의 단발성 신경절신경종

The Solitary Polypoid Ganglioneuroma of the Ascending Colon

  • 정용욱 (영남대학교 의과대학 내과학교실) ;
  • 장병익 (영남대학교 의과대학 내과학교실) ;
  • 장경애 (영남대학교 의과대학 내과학교실) ;
  • 김경옥 (영남대학교 의과대학 내과학교실) ;
  • 김미진 (영남대학교 의과대학 병리학교실)
  • Jung, Yong-Wook (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Jang, Byung-Ik (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Chang, Kyung-Ae (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Kim, Kyeong-Ok (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Kim, Mi-Jin (Department of Pathology, Yeungnam University College of Medicine)
  • 투고 : 2010.05.18
  • 심사 : 2010.10.12
  • 발행 : 2010.12.30
⟨ 이전 논문 다음 논문 ⟩

초록

신경절신경종은 신경외배엽 종양으로 신경절 세포, 신경 섬유 그리고 장관신경계를 지지하는 세포들로 구성된다. 신경절신경종은 우리 몸의 어느곳에서나 발생할 수 있지만, 신경절 신경종이 위장관에서 발생하는 경우는 매우 드물다. 50세 남자가 개인 병원에서 시행한 복부초음파검사에서 간 및 부신에 종괴가 발견되어 전원되었다. 입원 후 복부 자기공명촬영 시행 후 간조직검사를 시행하였고, 소 결절성 과증식으로 진단되었다. 환자가 원하여 시행한 대장 내시경검사상 0.3~0.8 cm 크기의 용종이 6개 있었고, 상행결장에 있던 0.6 cm크기의 아유경성 용종을 제외한 나머지는 선종으로 진단되었다. 상행결장의 용종은 현미경 검사상 신경 섬유와 신경절세포들의 증식이 점막에서 관찰되었고, S-100 염색에 양성 소견을 보여 단발성 신경절신경종으로 진단되었다. 저자들은 전신 질환 없이 내시경으로 우연히 발견한 결장의 단발성 신경절신경종을 경험하여 보고한다.

Ganglioneuromas are neuroectodermal tumors composed of varying amount of ganglion cells, nerve fibers, supporting cells of the enteric nervous system. Ganglioneuromas of the GI tract are rare tumors. A 50-year-old man came to our hospital due to the mass of liver and adrenal gland which was examined with ultrasonography at local medical center. On admission, abdominal magnetic resonance imaging was taken and liver biopsy was done. The mass of liver was hyperplastic nodule. At colonoscopy, about 0.3~0.8 cm sized six polyps were noted. Except the 0.6 cm sized semipedunculated polyp of the ascending colon, the others were tubular adenomas. Histological examination of the polyp of the ascending colon revealed localized proliferation of nerve fibers and ganglion cells. These cells are positive for S-100 protein by immunihistochemistry. Therefore, he was diagnosed with polypoid ganglioneuroma of the ascending colon. We report this case because the solitary ganglioneuroma in large intestine without systemic disease was rare.

키워드

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