The Korean Journal of Medicine

  • 제79권6호
  • /
  • Pages.720-723
  • /
  • 2010
  • /
  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지

Neisseria elongata subsp. nitroreducens에 의한 인공판막 심내막염

A case of prosthetic valve endocarditis due to Neisseria elongata subsp. nitroreducens

  • 박동진 (전남대학교 의과대학 내과학교실) ;
  • 정숙인 (전남대학교 의과대학 내과학교실) ;
  • 정영선 (전남대학교 의과대학 내과학교실) ;
  • 장희창 (전남대학교 의과대학 내과학교실) ;
  • 박경화 (전남대학교 의과대학 내과학교실) ;
  • 윤현주 (전남대학교 의과대학 내과학교실) ;
  • 신종희 (전남대학교 의과대학 진단검사의학교실)
  • Park, Dong-Jin (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Jung, Sook-In (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Jung, Young-Sun (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Jang, Hee-Chang (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Park, Kyung-Hwa (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Yoon, Hyun-Ju (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Shin, Jong-Hee (Department of Laboratory Medicine, Chonnam National University Medical School)
  • 투고 : 2009.09.24
  • 심사 : 2010.01.04
  • 발행 : 2010.12.01
⟨ 이전 논문 다음 논문 ⟩

초록

N. elongata subsp. nitroreducens는 비인두강의 상재균이지만 기저 심장 질환이 있거나 치과 시술을 받은 환자에서 드물게 심내막염을 일으킬 수 있다. 저자들은 인공판막을 가진 환자에서 발생한 N. elongata subsp. nitroreducens에 의한 감염성 심내막염을 진단하고 수술적 치료 없이 항생제 치료만으로 호전된 1예를 경험하였기에 보고하는 바이다.

Infective endocarditis due to Neisseria elongata subsp. nitroreducens occurs infrequently. In this report, we describe a case of infective endocarditis caused by N. elongata subsp. nitroreducens in a patient with a prosthetic heart valve. A 55-year-old woman presented with complaints of fever and headache that she had been experiencing over the course of 4 weeks. Transesophageal echocardiography showed vegetation on the prosthetic mitral valve. A blood culture isolate was confirmed as N. elongata subsp. nitroreducens using biochemical characterization and DNA sequencing of 16S rRNA. The clinical manifestations improved with medical treatment.

키워드

참고문헌

  1. Bovre K, Holten E. Neisseria elongata sp. nov., a rod-shaped member of the genus neisseria: re-evaluation of cell shape as a criterion in classification. J Gen Microbiol 60:67-75, 1970 https://doi.org/10.1099/00221287-60-1-67
  2. Grant PE, Brenner DJ, Steigerwalt AG, Hollis DG, Weaver RE. Neisseria elongata subsp. nitroreducens subsp. nov., formerly CDC group M-6, a gram negative bacterium associated with endocarditis. J Clin Microbiol 28:2591-2596, 1990
  3. Hsiao JF, Lee MH, Chia JH, Ho WJ, Chu JJ, Chu PH. Neisseria elongata endocarditis complicated by brain embolism and abscess. J Med Microbiol 57:376-381, 2008 https://doi.org/10.1099/jmm.0.47493-0
  4. 원선영, 정두련, 주광로, 이미숙, 조용균, 김은옥, 김양수, 우준희, 배직현. Neisseria elongata subsp. nitroreducens에 의한 감염성 심내막염 1예. 대한화학요법학회지 16:105-109, 1998
  5. Hoshino T, Ohkusu K, Sudo F, Nakajima H, Ishiwada N, Ezaki T, Kohno Y. Neisseria elongata subsp. nitroreducens endocarditis in a seven-year-old boy. Pediatr Infect Dis J 24;391-392, 2005 https://doi.org/10.1097/01.inf.0000157350.32886.ae
  6. Durack DT, Lukes AS, Bright DK. New criteria diagnosis of infective endocarditis: utilization of specific echocardiographic findings: duke endocarditis service. Am J Med 96:200-209, 1994 https://doi.org/10.1016/0002-9343(94)90143-0
  7. Li JS, Sexton DJ, Mick N, Nettles R, Fowler VG Jr, Ryan T, Bashore T, Corey GR. Proposed modifications to the duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis 30:633-638, 2000 https://doi.org/10.1086/313753
  8. Wong JD, Janda JM. Association of an important Neisseria species. Neisseria elongata subsp. nitroreducens, with bacteremia, endocarditis, and osteomyelitis. J Clin Microbiol 30:719-720, 1992
  9. 손경목, 고관수, 김정, 이지영, 오원섭, 백경란, 송재훈. 감염성 심내막염 환자에서 16S rRNA 유전자 염기서열 분석을 통한 Gemella 동정 2예. 대한내과학회지 70:591-596, 2006
  10. 강용운, 정영선, 박경화, 정숙인, 신종희, 안병희, 고관수. 다발성 골수종 환자에서 척추염을 동반한 브루셀라 심내막염. 대한내과학회지 74:561-565, 2008
  11. Rossau R, Vandenbussche G, Thielemann S, Segers P, Grosch H, Gothe E, Mannheim W, de Ley J. Ribosomal ribonucleic acid cistron similarities and deoxyribonucleic acid homologies of Neisseria, Kingella, Eikenella, Simonsiella, Alysiella, and Centers for Disease Control groups EF-4 and M-5 in the emended family Neisseriaceae. Int J Syst Bacteriol 39:185-198, 1989 https://doi.org/10.1099/00207713-39-2-185
  12. Andersen BM, Weyant RS, Steigerwalt AG, Moss CW, Hollis DG, Weaver RE, Ashford D, Brenner DJ. Characterization of Neisseria elongata subsp: glycolytica isolates obtained from human wound specimens and blood cultures. J Clin Microbiol 33:76-78, 1995
  13. Dominguez EA, Smith TL. Endocarditis due to Neisseria elongata subspecies nitroreducens: case report and review. Clin Infect Dis 26:1471-1473, 1998 https://doi.org/10.1086/517671
  14. Evans M, Yazdani F, Malnick H, Shah JJ, Turner DP. Prosthetic valve endocarditis due to Neisseria elongata subsp: elongata in a patient with Klinefelter's syndrome. J Med Microbiol 56:860-862, 2007 https://doi.org/10.1099/jmm.0.47155-0
  15. Picu C, Mille C, Popescu GA, Bret L, Prazuck T. Aortic prosthetic endocarditis with Neisseria elongata subspecies nitroreducens. Scand J Infect Dis 35:280-282, 2003 https://doi.org/10.1080/0036554021000027003
  16. Haddow LJ, Mulgrew C, Ansari A, Miell J, Jackson G, Malnick H, Rao GG. Neisseria elongata endocarditis: case report and literature review. Clin Microbiol Infect 9:426-430, 2003 https://doi.org/10.1046/j.1469-0691.2003.00533.x
  17. 김민규, 송재관, 강덕현, 이재환, 조윤행, 박경하, 고관호. 감염성 심내막염의 최신 임상 경향. 대한내과학회지 58:28-38, 2000
  18. Kaplan LJ, Flaherty J. Centers for Disease Control Group M-6: a cause of destructive endocarditis. J Infect Dis 164:822-823, 1991 https://doi.org/10.1093/infdis/164.4.822