The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

Neurolymphomatosis in a patient with T-cell non-Hodgkin's lymphoma

T 세포 림프종 환자에서 발생한 신경림프종증 1예

  • Sung, Pil-Soo (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Jun, Byoung-Yun (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Ha-Wook (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Jung, Mo-Eun (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Ji-Chan (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lee, Yeon-Su (Department of Diagnostic Radiology, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Suk-Young (Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 성필수 (가톨릭대학교 의과대학 대전성모병원 내과) ;
  • 전병연 (가톨릭대학교 의과대학 대전성모병원 내과) ;
  • 박하욱 (가톨릭대학교 의과대학 대전성모병원 내과) ;
  • 정모은 (가톨릭대학교 의과대학 대전성모병원 내과) ;
  • 박지찬 (가톨릭대학교 의과대학 대전성모병원 내과) ;
  • 이연수 (가톨릭대학교 의과대학 대전성모병원 영상의학과) ;
  • 박석영 (가톨릭대학교 의과대학 대전성모병원 내과)
  • Received : 2009.10.20
  • Accepted : 2010.01.04
  • Published : 2010.12.01
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Abstract

Neurolymphomatosis, defined as a selective infiltration of lymphoma cells into cranial nerves, peripheral nerves and nerve roots, is a rarely recognized manifestation of lymphoma. Its characteristic symptoms are often overlooked or mistaken for other conditions, such as a peripheral polyneuropathy, due to chemotherapeutic agents or clinical findings of metastatic lesions in the central nervous system. Recently, neurolymphomatosis has been increasingly recognized using magnetic resonance imaging and positron emission tomography-computed tomography. We present a case of neurolymphomatosis manifesting as peripheral mononeuropathy in a patient with T-cell non-Hodgkin's lymphoma.

신경림프종증은 림프종 세포가 뇌신경을 포함한 말초 신경계를 침범하는 드문 질환이다. 신경림프종증은 최근 영상 의학적인 방법을 통하여 진단율이 높아지고는 있으나, 진단이 지연되는 경우가 흔하다. 저자들은 T 세포 림프종 치료도중 수근 하수 증상이 나타난 신경림프종증 환자의 증례를 문헌고찰과 함께 보고하는 바이다.

Keywords

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