Abstract
A 37-year-old male patient presented with a fever, chills, and abdominal pain. The patient was diagnosed with Typhoid fever based on blood culture, but did not clinically respond to standard antibiotic (Ceftriaxone) therapy. On day 9, leptospira serology was positive and doxycycline was added to the treatment strategy. With combination therapy, the patient recovered from the infection. In most cases, similar clinical presentations make the diagnosis of concurrent infections of febrile diseases difficult, and serious complications can develop as a consequence of delayed treatment. As with this case, if the patient initially has serious a medical condition caused by complications, and does not clinically respond to initial standard antibiotics therapy or has an unusual course of disease, concurrent infection must be considered.
열성 질환의 동시감염은 각 질환의 유사한 임상양상으로 인하여 진단 및 치료에 있어 혼란을 가져온다. 국내 및 해외학회에서는 동시감염으로 인해 진단 및 치료에 있어서 어려움이 있었던 예들이 보고되어지고 있으나 장티푸스와 렙토스피라병의 동시감염은 아직 보고된 바가 없었다. 저자들은 초기 항생제 치료에 반응을 보이지 않았던 장티푸스에서 렙토스피라병의 동시감염을 진단하였고, 항생제 병용으로 치료한 1예를 경험하였기에 보고하는 바이다.