The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

Screening for Lung Cancer

폐암의 조기진단

  • Kim, Hyae-Young (Department of Radiology, Center for Lung Cancer, National Cancer Center)
  • 김혜영 (국립암센터 폐암센터 영상의학과)
  • Published : 2010.09.01
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Abstract

Lung cancer is the primary cause of cancer mortality in worldwide. However, early lung cancer screening with chest radiography and sputum cytology in 1970s, have failed in reduction of lung cancer mortality, despite the higher proportion of early-stage cancer detection on screening. Therefore, screening for lung cancer has not been recommended. Low dose CT has been recently assessed as a screening tool in observational studies suggesting better impaction than the one obtained with chest radiography. Eight randomized controlled trials are currently under way to evaluate low dose CT as a screening tool for lung cancer. No current data exist to suggest that lung cancer screening with CT will reduce lung cancer mortality.

폐암을 조기에 발견하는 것이 가능한가라고 질문한다면 아마도 그 대답은 "예"일 것이다. 그러나 폐암의 검진으로 폐암에 의한 사망률을 감소시킬 수 있는가 혹은 바꾸어 말해서 "폐암 검진이 효과가 있을까"라고 질문한다면 "아직까지는 밝혀진 바 없다"라고 하는 것이 적절한 대답일 것이다. 현재까지 저선량 CT 사용을 폐암 검진에 권장해야 한다는 과학적 증거는 없다. 그러나 저선량 CT를 이용하여 폐암 검진을 시행한 결과 흡연과 관련된 질환에 대한 이해와 폐암의 생명 작용(biology)에 대해서 좀 더 알게 된 것은 사실이다. 최종 목표를 검진으로 인한 폐암의 사망률 감소는 현재 진행되고 있는 RCT의 좀더 장기적인 추적검사가 필요하며 RCT의 결과가 나올 때까지 개별적으로 검진하는 것은 피해야 한다는 것이 권장 사항이다.

Keywords

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