Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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1,3-Dichloro-5,5-dimethylhydantoin as a Novel and Efficient Homogeneous Catalyst in Biginelli Reaction

  • Received : 2010.08.10
  • Accepted : 2010.09.13
  • Published : 2010.11.20
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Abstract

A new and efficient method for the preparation of substituted 3,4-dihydropyrimidin-2(1H)-ones via Biginelli synthesis using catalytic amounts of 1,3-dichloro-5,5-dimethylhydantoin is presented. Short reaction times, easy work-up, high yields of products and stability, easy-handling, non-toxicity and cheapness of the catalyst are noteworthy advantages of the present work.

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References

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