References
- Mao L, Hong WK, Papadimitrakopoulou VA : Focus on head and neck cancer. Cancer Cell 5 : 311, 2004. https://doi.org/10.1016/S1535-6108(04)00090-X
- Jemal A, Siegel R, Ward E et al : Cancer statistics. CA Cancer J Clin 56 : 106, 2006. https://doi.org/10.3322/canjclin.56.2.106
- Freier K, Bosch FX, Flechtenmacher C et al : Distinct site-specific oncoprotein overexpression in head and neck squamous cell carcinoma: a tissue microarray analysis. Anticancer Res 23 : 3971, 2003.
- Vogelstein B, Kinzler KW : The multistep nature of cancer. Trends Genet. 1993, p.138.
- Schoell WMJ, Janicek MR, Mirhashemi R : Epidemiology and biology of cervical cancer. Semin Surg Oncol 16 : 1999.
- Rubin Grandis J, Melhem MF, Gooding WE : Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer lnst 90 : 824, 1998. https://doi.org/10.1093/jnci/90.11.824
- Maurizi M, Almadori G, Ferrandina G et al : Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. Brit J Cancer 74 : 1253, 1996. https://doi.org/10.1038/bjc.1996.525
- Sathyan KM, Nalinakumari KR, Abraham T : Influence of single nucleotide polymorphisms in H-Ras and eyclin D1 genes on oral cancer susceptibility. Oral Oncol 42 : 607, 2006. https://doi.org/10.1016/j.oraloncology.2005.10.019
- Auerkari El : Methylation of tumor suppressor genes p16(lNK4a), p27(Kip1) and E-cadherin in carcinogenesis. Oral Oncol 42 : 5, 2006. https://doi.org/10.1016/j.ooe.2005.05.007
- Wang L, Liu T, Nishioka M : Activation of ERK1/2 and cyelin D1 expression in oral tongue squamous cell carcinomas: relationship between clinicopathological appearances and cell proliferation. Oral Oncol 42 : 625 2006. https://doi.org/10.1016/j.oraloncology.2005.11.002
- He Y, Zeng Q, Drenning SD et al : Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter. J Natl Cancer Inst 90 : 1080, 1998. https://doi.org/10.1093/jnci/90.14.1080
- Caponigro F, Milano A, Basile M : Recent advances in head and neck cancer therapy: the role of new cytotoxic and molecular-targeted agents. Curr Opin Oncol 18 : 247, 2006. https://doi.org/10.1097/01.cco.0000219253.53091.fb
- Glover DM, Leibowitz MH, McLean DA : Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 81 : 95, 1995. https://doi.org/10.1016/0092-8674(95)90374-7
- Schumacher JM, Ashcroft N, Donovan PJ : A highly can served centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos. Development 125 : 4391, 1998.
- Schumacher JM, Golden A, Donovan PJ : AIR-2:An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J Cell BioI 143 : 1635, 1998. https://doi.org/10.1083/jcb.143.6.1635
- Mesilaty-Gross S, Reich A. Motro B : The Drosophila STAM gene homolog is in a tight gene cluster. and its expression correlates to that of the adjacent gene ial. Gene 231 : 173, 1999. https://doi.org/10.1016/S0378-1119(99)00053-0
- Roghi C, Giet R, Uzbekov R : The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly. J Cell Sci 111 : 557, 1998.
- Adams RR, Wheatley SP, Gouldsworthy AM et al : INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr Biol 10 : 1075, 2000. https://doi.org/10.1016/S0960-9822(00)00673-4
- Nigg EA : Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell BioI 2 : 21, 2001.
- Marumoto T. Honda S, Hara T : Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells. J Biol Chem 278 : 51786, 2003. https://doi.org/10.1074/jbc.M306275200
- Sen S. Zhou H. White RA : A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines. Oncogene 14 : 2195. 1997. https://doi.org/10.1038/sj.onc.1201065
- Tanner M, Grenman S, Koul A et al : Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin. Cancer Res. 6 : 1833, 2000.
- Harrington EA, Bebbington D, Moore J : VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo. Nat Med 10 : 262, 2004. https://doi.org/10.1038/nm1003
- Ditchfield C, Johnson VL, Tighe A : Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell BioI 161 : 267, 2003. https://doi.org/10.1083/jcb.200208091
- Mitelman F, Johansson B, Mertens F : Catalog of Chromosome Aberrations in Cancer. New York, Wiley-Liss, 1994, p.11.
- Zhou B, Elledge SJ : The DNA damage response: putting checkpoints in perspective. Nature (Lond.) 408 : 433, 2000. https://doi.org/10.1038/35044005
- CW Lee : Cell cycle checkpoint control. Exp. Mol. Med 33 : 39, 2001.
- Sakai H : Microtubules in mitosis. Cell Struct. Funct 19 : 57, 1994. https://doi.org/10.1247/csf.19.57
- Kellogg DR, Moritz M, Alberts BM : The centrosome and cellular organization. Annu. Rev. Biochem 63 : 639, 1994. https://doi.org/10.1146/annurev.bi.63.070194.003231
- Bayliss R, Sardon T, Vernos I : Structural basis or Aurora-A activation by TPX2 at the mitotic spindle. Mol Cell 12 : 851, 2003. https://doi.org/10.1016/S1097-2765(03)00392-7
- Fu J, Bian M, Jiang Q : Roles of Aurora Kinases in Mitosis and Tumorigenesis. Mol Cancer Res 5 : 1, 2007. https://doi.org/10.1158/1541-7786.MCR-06-0208
- Meraldi P, Honda R, Nigg EA : Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53/ cells. EMBO J 21 : 483, 2002. https://doi.org/10.1093/emboj/21.4.483
- Anand S, Penrhyn-Lowe S, Venkitaraman AR : AURORA-A amplification overrides the mitotic spindle assembly checkpoint. inducing resistance to Taxol. Cancer Cell 3 : 51, 2003. https://doi.org/10.1016/S1535-6108(02)00235-0
- Katayama H, Sasai K, Kawai H : Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet 36 : 55, 2004. https://doi.org/10.1038/ng1279
- Twu NF, Yuan CC, Yen MS et al : Expression of Aurora kinase A and B in normal and malignant cervical tissue: high Aurora A kinase expression in squamous cervical cancer. Eur J Obstet Gynecol Reprod BioI 142 : 57, 2009. https://doi.org/10.1016/j.ejogrb.2008.09.012