Journal of the Korean Society of Physical Medicine (대한물리의학회지)

The Korean Society of Physical Medicine (대한물리의학회)
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Effects of Electroacupuncture on Activity of GOT, GPT, LDH and Functional Recovery in the Motor Injury Rats by the 6-hydroxydopamine

6-hydroxydopamine에 의한 운동손상 흰 쥐에서 전침이 GOT, GPT, LDH 활성도 및 기능회복에 미치는 영향

  • Ha, Mi-Sook (Department of Physical Therapy, Masan University) ;
  • Rho, Min-Hee (Department of Physical Therapy, Pusan Catholic University)
  • 하미숙 (마산대학 물리치료과) ;
  • 노민희 (부산가톨릭대학교 물리치료학과)
  • Received : 2010.03.29
  • Accepted : 2010.05.23
  • Published : 2010.05.31
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Abstract

Purpose : This study was investigated the effect of electroacupuncture stimulation on the change of blood biochemical components in the rat spinal cord injury(SCI) damaged by the 6-hydroxydopamine. Methods : SCI model rats were damaged in L1-L2 injected with 6-hydroxydopamine. The thirty Sprague-Dawley adult male rats were randomly divided into normal group, control group and electroacupuncture group. Experimental groups were applied as electroacupuncture(Es-160, ITO, Japan) for 15minutes during the low frequency(2 Hz) stimulation to zusanli. The enzyme concentration levels analysis of the hematological changes were measured of Glutamate Oxaloacetate Transaminase(GOT), Glutamate Pyruvate Transaminase(GPT), Lactate dehydrogenase(LDH) and motor function recovery change was evaluated by the rota-rod test. Results : This study were as follow : The concentration of GOT, LDH in experimental group was lower than control group(p<.05). The experimental group showed increase of motor function recovery more in compared to control group(p<.05). Conclusion : The results of this study showed that electroacupuncture to zusanli point have an effect on functional recovery after the 6-hydroxydopamine induced SCI in rats.

Keywords

References

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