References
- Bafor M, Stobart AK, Stymne S (1990) Properties of the glycerol acylating enzymes in microsomal preparations from the developing seeds of safflower (Carthamus tinctorius) and turnip rape (Brassica campestris) and their ability to assemble cocoa-butter type fats. J Am Oil Chem Soc 67:217-225 https://doi.org/10.1007/BF02540647
- Banas A, Dahlqvist A, Stahl U, Lenman M, Stymne S (2000) The involvement of phospholipid:diacylglycerol acyltransferases in triacylglycerol production. Biochem Soc Trans 28:703-705 https://doi.org/10.1042/BST0280703
- Bates PD, Ohlrogge JB, Pollard M (2007) Incorporation of newly synthesized fatty acids into cytosolic glycerolipids in pea leaves occurs via acyl editing. J Biol Chem 282:31206-31216 https://doi.org/10.1074/jbc.M705447200
- Beisson F, Li Y, Bonaventure G, Pollard M, Ohlrogge JB (2007) The acyltransferase GPAT5 is required for the synthesis of suberin in seed coat and root of Arabidopsis. Plant Cell 19:351-368 https://doi.org/10.1105/tpc.106.048033
- Bernerth R, Frentzen M (1990) Utilization of erucoyl-CoA by acyltransferases from developing seeds of Brassica napus L. involved in triacylglycerol biosynthesis. Plant Sci 67:21-28 https://doi.org/10.1016/0168-9452(90)90046-Q
- Brokerhoff H, Yurkowski M (1966) Stereospecific analyses of several vegetable fats. J Lipid Res 7:62-64
- Brough CL, Coventry JM, Christie WW, Kroon JT, Brown AP, Barsby TL, Slabas AR (1996) Towards the genetic engineering of triacylglycerols of defined fatty acid composition: major changes in erucic acid content at the sn-2 position affected by the introduction of a 1-acyl-sn-glycerol-3-phosphate acyltransferase from Limnanthes douglasii into oil seed rape. Mol Breed 2:133-142 https://doi.org/10.1007/BF00441428
- Brown AP, Slabas AR, Denton H (2002) Substrate selectivity of plant and microbial lysophosphatidic acid acyltransferases. Phytochemistry 61:493-501 https://doi.org/10.1016/S0031-9422(02)00290-X
- Burgal J, Shockey J, Lu C, Dyer J, Larson T, Graham I, Browse J (2008) Metabolic engineering of hydroxy fatty acid production in plants: RcDGAT2 drives dramatic increases in ricinoleate levels in seed oil. Plant Biotechnol J 6:819-831 https://doi.org/10.1111/j.1467-7652.2008.00361.x
- Cahoon EB, Shockey JM, Dietrich CR, Gidda SK, Mullen RT and Dyer JM (2007) Engineering oilseeds for sustainable production of industrial and nutritional feedstocks: solving bottlenecks in fatty acid flux. Curr Opin Plant Biol 10:236-244 https://doi.org/10.1016/j.pbi.2007.04.005
- Cao YZ, Oo KC, Huang AH (1990) Lysophosphatidate acyltransferase in the microsomes from maturing seeds of meadowfoam (Limnanthes alba). Plant Physiol 94:1199-1206 https://doi.org/10.1104/pp.94.3.1199
- Christie WW, Nikolova-Damyanova B, Laakso P, Herslof B (1991) Stereospecific analysis of triacyl-sn-glycerols via resolution of diastereomeric diacylglycerol derivatives by high performance liquid chromatography on silica. J Am Oil Chem Soc 68:695-701 https://doi.org/10.1007/BF02662155
- Dahlqvist A, Stahl U, Lenman M, Banas A, Lee M, Sandager L, Ronne H, Stymne S (2000) Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants. Proc Natl Acad Sci USA 97:6487-6492 https://doi.org/10.1073/pnas.120067297
- Davies HM, Hawkins DJ, Nelsen JS (1995) Lysophosphatidic acid acyltransferase from immature coconut endosperm having medium chain length substrate specificity. Phytochemistry 39:989-996 https://doi.org/10.1016/0031-9422(95)00046-A
- Drexler H, Spiekermann P, Meyer A, Domergue F, Zank T, Sperling P, Abbadi A, Heinz E (2003) Metabolic engineering of fatty acids for breeding of new oilseed crops: strategies, problems and first results. J Plant Physiol 160:779-802 https://doi.org/10.1078/0176-1617-01025
-
Dutta PC, Appelqvist L Stymne S (1992) Utilization of petroselinate (C18:1
${\Delta}$ 6) by glycerol acylation enzymes in microsomal preparations of developing embryos of carrot (Daucus carota L.), safflower (Carthamus tinctorius L.) and oil rape (Brassica napus L.) Plant Sci 81:57-64 https://doi.org/10.1016/0168-9452(92)90024-G - Frentzen M (1993) Acyltransferases and triacylglycerols. In: T.S. Moore Jr., Editor, Lipid Metabolism in plants. CRC Press, 195-230
- Furukawa-Stoffer TL, Boyle RM, Thomson AL, Sarna MA, Weselake RJ (2003) Properties of lysophosphatidylcholine acyltransferase from Brassica napus cultures. Lipids 38:651-656 https://doi.org/10.1007/s11745-003-1110-0
- He X, Turner C, Chen GQ, Lin JT, McKeon TA (2004) Cloning and characterization of a cDNA encoding diacylglycerol acyltransferase from castor bean. Lipids 39:311-318 https://doi.org/10.1007/s11745-004-1234-2
- Ichihara K, Takahashi T, Fujii S (1988) Diacylglycerol acyltransferase in maturing safflower seeds - its influences on the fatty acid composition of triacylglycerol and on the rate of triacylglycerol synthesis. Biochim Biophys Acta 958:125-129 https://doi.org/10.1016/0005-2760(88)90253-6
- Ichihara K, Mae K, Sano Y, Tanaka K (1995) 1-Acylglycerophos phocholine O-acyltransferase in maturing safflower seeds. Planta 196:551-557
- Ichihara K, Noda M (1982) Some properties of diacylglycerol acyltransferase in a particulate fraction from maturing saf-flower seeds. Phytochemistry 21: 1895-1901 https://doi.org/10.1016/0031-9422(82)83010-0
- Jako C, Kumar A, Wei Y, Zou J, Barton DL, Giblin EM, Covello PS, Taylor DC (2001) Seed-specific over-expression of an Arabidopsis cDNA encoding a diacylglycerol acyltransferase enhances seed oil content and seed weight. Plant Physiol 126:861-874 https://doi.org/10.1104/pp.126.2.861
- Katavic V, Reed DW, Taylor DC, Giblin EM, Barton DL, Zou J, Mackenzie SL, Covello PS, Kunst L (1995) Alteration of seed fatty acid composition by an ethyl methanesulfonate-induced mutation in Arabidopsis thaliana affecting diacylglycerol acyltransferase activity. Plant Physiol 108:399-409 https://doi.org/10.1104/pp.108.1.399
- Katavic V, Friesen W, Barton DL, Gossen KK, Giblin EM, Luciw T, An J, Zou J, MacKenzie SL, Keller WA, Males D Taylor DC (2001) Improving erucic acid content in rapeseed through biotechnology: What can the Arabidopsis FAE1 and the yeast SLC1-1 genes contribute? Crop Sci 41:739-747 https://doi.org/10.2135/cropsci2001.413739x
- Kennedy EP (1961) Biosynthesis of complex lipids. Fed Proc Am Soc Exp Biol 20:934-940
- Kim HU, Li Y, Huang AH (2005) Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis. Plant Cell 17:1073-1089 https://doi.org/10.1105/tpc.104.030403
- Knutzon DS, Hayes TR, Wyrick A, Xiong H, Maelor Davies H, Voelker TA (1999) Lysophosphatidic acid acyltransferase from coconut mediates the insertion of laurate at the sn-2 position of triacylglycerols in lauric rapeseed oil and can increase total laurate levels. Plant Physiol 120:739-746 https://doi.org/10.1104/pp.120.3.739
- Lands WE (1960) Metabolism of glycerolipids. 2. Enzymatic acylation of lysolecithin. J Biol Chem 235:2233-2237
- Larson TR, Edgell T, Byrne J, Dehesh K, Graham IA (2002) Acyl-CoA profiles of transgenic plants that accumulate medium-chain fatty acids indicate inefficient storage lipid synthesis in developing oilseeds. Plant J 32:519-527 https://doi.org/10.1046/j.1365-313X.2002.01440.x
- Lassner MW, Levering CK, Davies HM, Knutzon DS (1995) Lysophophatidic acid acyltransferase from meadowfoam mediates insertion of erucic acid at the sn-2 position of triacylglycerol in transgenic rapeseed oil. Plant Physiol 109:1389-1394 https://doi.org/10.1104/pp.109.4.1389
- Laurent P, Huang AH (1992) Organ- and development-specific acyl coenzyme A lysophosphatidate acyltransferases in palm and meadowfoam. Plant Physiol 99:1711-1715 https://doi.org/10.1104/pp.99.4.1711
- Lee KR, Kim HU (2009) Metabolic engineering for production of industrial oils in transgenic plants. J Plant Biotechnol 36:97-105 https://doi.org/10.5010/JPB.2009.36.2.097
- Li Y, Beisson F, Koo AJ, Molina I, Pollard M, Ohlrogge J (2007) Identification of acyltransferases required for cutin biosynthesis and production of cutin with suberin-like monomers. Proc Natl Acad Sci USA 104:18339-18344 https://doi.org/10.1073/pnas.0706984104
- Lisa M, Holcapek M (2008) Triacylglycerols profiling in plant oils important in food industry, dietetics and cosmetics using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. J Chromatogr A 1198-1199:115-130 https://doi.org/10.1016/j.chroma.2008.05.037
- Lohden I, Frentzen M (1992) Triacylglycerol biosynthesis in developing seeds of Tropaeolum majus L. and Limnanthes douglasii R. Br. Planta 188:215-224 https://doi.org/10.1007/BF00216816
- Lu C, Xin Z, Ren Z, Miquel M, Browse J (2009) An enzyme regulating triacylglycerol composition is encoded by the ROD1 gene of Arabidopsis. Proc Natl Acad Sci USA 106:18837-18842 https://doi.org/10.1073/pnas.0908848106
- Lung SC, Weselake RJ (2006) Diacylglycerol acyltransferase: a key mediator of plant triacylglycerol synthesis. Lipids 41:1073-1088 https://doi.org/10.1007/s11745-006-5057-y
- Martin BA, Wilson RF (1983) Properties of diacylglycerol acyltransferase from spinach leaves. Lipids 18:1-6 https://doi.org/10.1007/BF02534682
- Mhaske V, Beldjilali K, Ohlrogge J, Pollard M (2005) Isolation and characterization of an Arabidopsis thaliana knockout line for phospholipid:diacylglycerol transacylase gene (At5g13640). Plant Physiol Biochem 43:413-417 https://doi.org/10.1016/j.plaphy.2005.01.013
- Napier JA, Graham IA (2010) Tailoring plant lipid composition: designer oilseeds come of age. Curr Opin in Plant Biol 13:1-8 https://doi.org/10.1016/j.pbi.2009.12.001
- Oo KC, Huang AH (1989) Lysophosphatidate acyltransferase activities in the microsomes from palm endosperm, maize scutellum, and rapeseed cotyledon of maturing seeds. Plant Physiol 91:1288-1295 https://doi.org/10.1104/pp.91.4.1288
- Perry HJ, Harwood JL (1993) Changes in the lipid content of developing seeds of Brassica napus. Phytochemistry 32:1411-1415 https://doi.org/10.1016/0031-9422(93)85148-K
- Shen W (2008) Functional study of lysophosphatidylcholine acyltransferase in Arabidopsis. Poster presented at 18th International Symposium on Plant Lipids, Bordeaux, France, July 20-25
- Shockey JM, Gidda SK, Chapital DC, Kuan JC, Dhanoa PK, Bland JM, Rothstein SJ, Mullen RT, Dyer JM (2006) Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum. Plant Cell 18:2294-2313 https://doi.org/10.1105/tpc.106.043695
- Siloto RM, Truksa M, Brownfield D, Good AG, Weselake RJ (2009) Directed evolution of acyl-CoA: diacylglycerol acyltransferase: development and characterization of Brassica napus DGAT1 mutagenized libraries. Plant Physiol Biochem 47:456-461 https://doi.org/10.1016/j.plaphy.2008.12.019
- Sorensen BM, Furukawa-Stoffer TL, Marshall KS, Page EK, Mir Z, Forster RJ, Weselake RJ. (2005) Storage lipid accumulation and acyltransferase action in developing flaxseed. Lipids 40:1043-1049 https://doi.org/10.1007/s11745-005-1467-0
- Stahl U, Carlsson AS, Lenman M, Dahlqvist A, Huang B, Banas W, Banas A, Stymne S (2004) Cloning and functional characterization of a phospholipid:diacylglycerol acyltransferase from Arabidopsis. Plant Physiol 135:1324-1335 https://doi.org/10.1104/pp.104.044354
- Stymne S, Stobart AK (1984) Evidence for the reversibility of the acyl-CoA-lysophosphatidylcholine acyltransferase in microsomal preparations from developing safflower (Carthamus tinctorius L.) cotyledons and rat liver. Biochem J 223:305-314 https://doi.org/10.1042/bj2230305
- Sugiura T, Kudo N, Ojima T, Kondo S, Yamashita A, Waku K (1995) Coenzyme A dependent modification of fatty acyl chains of rat liver membrane phospholipids - possible involvement of ATP independent acyl-CoA synthesis. J Lipid Res 36:440-450
- Suh MC, Schultz DJ, Ohlrogge JB (2002) What limits production of unusual monoenoic fatty acids in transgenic plants? Planta 215:584-595 https://doi.org/10.1007/s00425-002-0751-3
- Sun C, Cao YZ, Huang AH (1988) Acyl Coenzyme A preference of the glycerol phosphate pathway in the microsomes from the maturing seeds of palm, maize, and rapeseed. Plant Physiol 88:56-60 https://doi.org/10.1104/pp.88.1.56
- Taylor DC, Weber N, Barton DL, Underhill EW, Hogge LR, Weselake RJ, Pomeroy MK (1991) Triacylglycerol bioassembly in microspore-derived embryos of Brassica napus L. cv Reston. Plant Physiol 97:65-79 https://doi.org/10.1104/pp.97.1.65
- Taylor DC, Barton DL, Rioux KP, Mackenzie SL, Reed DW, Underhill EW, Pomeroy MK, Weber N (1992) Biosynthesis of acyl lipids containing very-long chain fatty acids in microspore-derived and zygotic embryos of Brassica napus L. cv Reston. Plant Physiol 99:1609-1618 https://doi.org/10.1104/pp.99.4.1609
- Taylor DC, Katavic V, Zou L, MacKenzie SL, Keller WA, An J, Friesen W, Barton DL, Pedersen KK, Giblin EM, Ge Y, Dauk M, Sonntag C, Luciw T, Males D (2002) Field testing of transgenic rapeseed cv. Hero transformed with a yeast sn-2 acyltransferase results in increased oil content, erucic acid content and seed yield. Mol Breed 8:317-322 https://doi.org/10.1023/A:1015234401080
- Taylor DC, Zhang Y, Kumar A, Francis T, Giblin EM, Barton DL, Ferrie JR, Laroche A, Shah S, Zhu W, Snyder CL, Hall L, Rakow G, Harwood JL, Weselake RJ (2009) Molecular modification of triacylglycerol accumulation by over-expression of DGAT1 to produce canola with increase seed oil content under field condition. Botany 87: 533-543 https://doi.org/10.1139/B08-101
- Voelker T, Kinney AJ (2001) Variations in the biosynthesis of seed storage lipids. Annu Rev Plant Physiol Plant Mol Biol 52:335-361 https://doi.org/10.1146/annurev.arplant.52.1.335
- Voelker TA, Hayes TR, Cranmer AM, Turner JC, Davies HM (1996) Genetic engineering of a quantitative trait - metabolic and genetic parameters influencing the accumulation of laurate in rapeseed. Plant J 9:229-241 https://doi.org/10.1046/j.1365-313X.1996.09020229.x
- Vogel G, Browse J (1996) Cholinephosphotransferase and diacylglycerol acyltransferase - substrate specificities at a key branch point in seed lipid metabolism. Plant Physiol 110:923-931 https://doi.org/10.1104/pp.110.3.923
- Weselake RJ, Shah S, Tang M, Quant PA, Snyder CL, Furukawa-Stoffer TL, Zhu W, Taylor DC, Zou J, Kumar A, Hall L, Laroche A, Rakow G, Raney P, Moloney MM, Harwood JL (2008) Metabolic control analysis is helpful for informed genetic manipulation of oilseed rape (Brassica napus) to increase seed oil content. J Exp Bot 59:3543-3549 https://doi.org/10.1093/jxb/ern206
- Wiberg E, Edwards P, Byrne J, Stymne S, Dehesh K (2000) The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L.. Planta 212:33-40 https://doi.org/10.1007/s004250000361
- Williams JP, Imperial V, Khan MU, Hodson JN (2000) The role of phosphatidylcholine in fatty acid exchange and desaturation in Brassica napus L. leaves. Biochem J 349:127-133 https://doi.org/10.1042/0264-6021:3490127
- Yu KS, McCracken CT Jr, Li R, Hildebrand DF (2006) Diacylglycerol acyltransferases from Vernonia and Stokesia prefer substrates with vernolic acid. Lipids 41:557-566 https://doi.org/10.1007/s11745-006-5005-x
- Zheng Z, Xia Q, Dauk M, Shen W, Selvaraj G, Zou J (2003) Arabidopsis AtGPAT1, a member of the membrane-bound glycerol-3-phosphate acytransferase gene family, is essential for tapetum differentiation and male fertility. Plant Cell 15:1872-1887 https://doi.org/10.1105/tpc.012427
- Zheng P, Allen WB, Roesler K, Williams ME, Zhang S, Li J, Glassman K, Ranch J, Nubel D, Solawetz W, Bhattramakki D, Llaca V, Deschamps S, Zhong GY, Tarczynski MC, Shen B (2008) A phenylalanine in DGAT is a key determinant of oil content and composition in maize. Nat Genet 40:367-372 https://doi.org/10.1038/ng.85
- Zou J, Katavic V, Giblin EM, Barton DL, MacKenzie SL, Keller WA, Hu X, Taylor DC (1997) Modification of seed oil content and acyl composition in the Brassicaceae by expression of a yeast sn-2 acyltransferase gene. Plant Cell 9:909-923 https://doi.org/10.1105/tpc.9.6.909