The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Effect of Herb Medicine Treatment for Functional Dyspepsia: A Randomized Placebo-Controlled and Compared Standard Treatment Trial

기능성 소화불량증 환자에 대한 한약복합제의 치료 효과: 무작위배정 표준치료제 위약 대조군 연구

  • Kim, Yeon-Mi (Dept. of Acupuncture and Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Park, Yang-Chun (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Jo, Jeong-Hyo (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kang, Wee-Chang (Dept. of Applicative Statistics, College of Economics, Daejeon University) ;
  • Son, Mi-Won (Dong-A Pharm. co., LTD.) ;
  • Hong, Kwon-Eui (Dept. of Acupuncture and Moxibustion, College of Oriental Medicine, Daejeon University)
  • 김연미 (대전대학교 한의과대학 침구학교실) ;
  • 박양춘 (대전대학교 한의과대학 내과학교실) ;
  • 조정효 (대전대학교 한의과대학 내과학교실) ;
  • 강위창 (대전대학교 경영대학 응용통계학) ;
  • 손미원 (동아제약) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실)
  • Received : 2009.01.07
  • Accepted : 2009.09.10
  • Published : 2010.01.30
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Abstract

Objective: Functional dyspepsia is a prevalent disease. It impedes subjective quality of life. The purpose of this study was to examine the equivalent effect of herb medicine treatment (DA-9701) for functional dyspepsia. Methods: In this randomized, single-blinded, placebo-controlled study, we compared a herb medicine (DA-9701) with standard treatment (mosapride) and placebo for the treatment of functional dyspepsia. 42 volunteers who satisfied the requirements were enrolled in study. Severity of dyspepsia was measured by Nepean Dyspepsia Index (NDI) and Functional Dyspepsia Quality of Life (FD-QOL) before and after treatments. Results: 1. In the DA-9701 group, total key symptoms score was significantly lower and improve rate of key symptoms was higher than in the mosapride and placebo groups, but there were no statistically significant differences between three groups. 2. In the DA-9701 and mosapride groups, "nausea" and "bad breath" were significantly lower compared with the placebo group. 3. In the DA-9701 group, NDI Quality of Life scores were significantly higher, but there were no [other] statistically significant differences between the three groups. 4. In the DA-9701 and mosapride groups, FD-QOL scores were higher compared with the placebo group, but there were no statistically significant differences between the three groups. Conclusion: Herb medicine treatment (DA-9701) is effective to improve the symptoms and quality of life in patients with functional dyspepsia.

Keywords

References

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