Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Isolation of Phenolics, Nucleosides, Saccharides and an Alkaloid from the root of Aralia cordata

  • Hyun, Sook-Kyung (Division of Food Science and Biotechnology, Pukyong National University) ;
  • Jung, Hyun-Ah (Division of Food Science and Biotechnology, Pukyong National University) ;
  • Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu) ;
  • Jung, Jee-H. (College of Pharmacy, Pusan National University) ;
  • Choi, Jae-Sue (Division of Food Science and Biotechnology, Pukyong National University)
  • Received : 2009.09.28
  • Accepted : 2010.03.08
  • Published : 2010.03.31
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Abstract

Fourteen compounds were isolated from the n-BuOH fraction of the roots of Aralia cordata (syn. = A. continentalis). Through spectroscopic method, the chemical structures were elucidated as: caffeic acid (1), protocatechuic acid (2), thymidine (3), uridine (4), methyl-$\alpha$-D-fructofuranoside (5), a mixture (3 : 1) of $\beta$-D-fructopyranoside and $\beta$-D-fructofuranoside (6), 1-methyl 1,2,3,4-tetrahydro-$\beta$-carboline-3-carboxylic acid (7), methyl-$\beta$-D-fructofuranoside (8), sucrose (9), 5-caffeoylquinic acid (chlorogenic acid) (10), 3-caffeoylquinic acid (neochlorogenic acid) (11), 4-caffeoylquinic acid (cryptochlorogenic acid) (12), 3,5-di-O-caffeoylquinic acid (13), and 1-kestose [$\beta$-D-fructofuranosyl-($2{\rightarrow}1$)-$\beta$-D-fructofuranosyl-($2{\rightarrow}1$)-$\alpha$-D-glucopyranoside] (14). Among them, compounds 5, 7, 8, and 10 - 14 were isolated from this plant for the first time.

Keywords

References

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