Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Depressive Conditions in Relation to Asthma Severity and Control

천식 환자에서 우울과 천식의 중증도 및 조절과의 관련성

  • Kim, Won-Jin (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Bae, Hyun-Sook (Department of Preventive and Occupational Medicine, Pusan National University School of Medicine) ;
  • Choi, Bo-Kyung (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Hwang, Jong-Min (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Shin, Kyung-Hwa (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Kim, Mi-Hyun (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Lee, Kwang-Ha (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Kim, Ki-Uk (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Jeon, Doo-Soo (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Park, Hye-Kyung (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Kim, Yun-Seong (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Lee, Min-Ki (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Park, Soon-Kew (Department of Internal Medicine, Pusan National University School of Medicine)
  • 김원진 (부산대학교 의학전문대학원 내과학교실) ;
  • 배현숙 (부산대학교 의학전문대학원 예방의학 및 산업의학교실) ;
  • 최보경 (부산대학교 의학전문대학원 내과학교실) ;
  • 황종민 (부산대학교 의학전문대학원 내과학교실) ;
  • 신경화 (부산대학교 의학전문대학원 내과학교실) ;
  • 김미현 (부산대학교 의학전문대학원 내과학교실) ;
  • 이광하 (부산대학교 의학전문대학원 내과학교실) ;
  • 김기욱 (부산대학교 의학전문대학원 내과학교실) ;
  • 전두수 (부산대학교 의학전문대학원 내과학교실) ;
  • 박혜경 (부산대학교 의학전문대학원 내과학교실) ;
  • 김윤성 (부산대학교 의학전문대학원 내과학교실) ;
  • 이민기 (부산대학교 의학전문대학원 내과학교실) ;
  • 박순규 (부산대학교 의학전문대학원 내과학교실)
  • Received : 2010.07.07
  • Accepted : 2010.08.09
  • Published : 2010.10.30
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Abstract

Background: Psychological factors are increasingly recognized for their influence on the course of asthma, on a worldwide basis. The aim of this study was to assess the presence of depression, anxiety, and asthma-related quality of life in patients with asthma and to evaluate their impact on severity and control of asthma. Methods: We assessed the severity of asthma by comparing patients' current medications to GINA guideline. The patients were classified into the controlled group (asthma patients with controlled disease) or into the uncontrolled group (asthma patients with uncontrolled disease), which included partly controlled and uncontrolled patients, again based on GINA guideline 2004. Patient-reported depressive symptoms, anxiety, and asthma-related quality of life were evaluated using the Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI), and Korean asthma quality of life (KAQLQ). Results: One hundred and twenty patients were enrolled (mean age, $55{\pm}1$ years; 65% women). Among the 120 patients, 14 (12%) patients were classified as having mild asthma, 88 (73%) as having moderate asthma, and 18 (15%) as having severe asthma. Eighty-one (67%) of the 120 patients were controlled. The asthma-related quality of life showed the difference according to severity of asthma (p=0.002). The prevalence of depression was lower (10% vs 26%, p=0.024) and the asthma-related quality of life was higher (59.951 (29~75) vs 35.103 (18~72), $p{\leq}0.001$) in the controlled group. Higher trait anxiety score and lower asthma-related quality of life were associated with depression (p<0.001, p=0.002, respectively). Conclusion: Psychological factors, such as anxiety and depression, are strongly associated with asthma control. Therefore, screening and management of depression is needed in patients with asthma.

Keywords

References

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