Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Fatal Hyperinfective Strongyloidiasis with Acute Respiratory Failure and Intestinal Perforation in Lung Cancer Patient

폐암환자에서 급성호흡부전과 장천공을 동반한 분선충 감염증 1예

  • Kim, Hyeon-Sik (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Kim, Yu-Eun (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Yun, Eun-Young (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Ju, Ji-Hyun (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Ma, Jeong-Eun (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Lee, Gi-Dong (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Cho, Yu-Ji (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Kim, Ho-Cheol (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Lee, Jong-Deok (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Hwang, Young-Sil (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Jeong, Yi-Yeong (Department of Internal Medicine, Gyeongsang National University School of Medicine)
  • 김현식 (경상대학교 의학전문대학원 내과학교실) ;
  • 김유은 (경상대학교 의학전문대학원 내과학교실) ;
  • 윤은영 (경상대학교 의학전문대학원 내과학교실) ;
  • 주지현 (경상대학교 의학전문대학원 내과학교실) ;
  • 마정은 (경상대학교 의학전문대학원 내과학교실) ;
  • 이기동 (경상대학교 의학전문대학원 내과학교실) ;
  • 조유지 (경상대학교 의학전문대학원 내과학교실) ;
  • 김호철 (경상대학교 의학전문대학원 내과학교실) ;
  • 이종덕 (경상대학교 의학전문대학원 내과학교실) ;
  • 황영실 (경상대학교 의학전문대학원 내과학교실) ;
  • 정이영 (경상대학교 의학전문대학원 내과학교실)
  • Received : 2009.08.03
  • Accepted : 2009.10.06
  • Published : 2010.01.30
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Abstract

Strongyloides stercoralis is an intestinal nematode that is a parasite to humans. The infecting filariform larvae of S. stercoralis enters the host body via the bloodstream, passes through the lungs, penetrates the alveoli, and then ascends the airway to transit down the esophagus into the small bowel. The infection can persist for decades without causing major symptoms and can elicit eosinophilia of varying magnitudes. Of note, this infection can also develop into a disseminated, often fatal, disease (hyperinfection) in patients receiving immunosuppressive corticosteroids. A 65-year-old man who was receiving corticosteroid therapy for the treatment of spinal stenosis was admitted to the emergency room with complaints of abdominal pain and severe dyspnea. We detected many S. stercoralis larvae in the sputum and in the bronchoalveolar-lavage sample collected by bronchoscopy. Here, we report a fatal case of strongyloidiasis with acute respiratory failure and intestinal perforation. In addition, we provide a brief review of the relevant medical literature.

Keywords

References

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