Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Central nervous system depressant effect of two spices ajowan (Carum copticum Karst.) and bay leaves (Cinnamomum tamala T.Nees.)

  • Rahman, T. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University) ;
  • Rahman, K.A. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University) ;
  • Rajia, S. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University) ;
  • Alamgir, M. (Pharmacy Discipline, Khulna University) ;
  • Khan, Mahmud T.H. (Department of Pharmacy, University of Science and Technology) ;
  • Choudhuri, M. Shahabuddin K. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University)
  • Received : 2008.03.07
  • Accepted : 2010.04.15
  • Published : 2010.06.30
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Abstract

Two common Indian spices Carum copticum Karst (ajowan) and Cinnamomum tamala T.Nees. (bay leaves) has been investigated first time to report the activity on the central nervous system. Preliminary study of the hot water extract showed depressant activity on the hole board test as evidenced from the ambulation and head dipping scores. The extracts further quicken the onset and increased the duration of pentobarbital induced sleeping time.

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References

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