Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Cutoff Values of Body Mass Index and Body Fat Measures for Metabolic Syndrome in Korean Population

한국인에서 대사증후군의 선별검사로서 체성분 분석 및 체질량지수의 타당성연구

  • Lee, Hyun-Jae (Department of Occupational and Environmental Medicine, College of Medicine, Dong-A University) ;
  • Kim, Byoung-Gwon (Department of Preventive Medicine, College of Medicine, Dong-A University) ;
  • Kim, Joon-Youn (Department of Preventive Medicine, College of Medicine, Dong-A University) ;
  • Kim, Jung-Man (Department of Preventive Medicine, College of Medicine, Dong-A University) ;
  • Yoo, Byung-Chul (Department of Preventive Medicine, College of Medicine, Kosin University) ;
  • Kim, Eun-Jeong (Department of Preventive Medicine, College of Medicine, Dong-A University) ;
  • Hong, Young-Seoub (Department of Preventive Medicine, College of Medicine, Dong-A University)
  • 이현재 (동아대학교 의료원 산업의학과) ;
  • 김병권 (동아대학교 의과대학 예방의학교실) ;
  • 김준연 (동아대학교 의과대학 예방의학교실) ;
  • 김정만 (동아대학교 의과대학 예방의학교실) ;
  • 유병철 (고신대학교 의과대학 예방의학교실) ;
  • 김은정 (동아대학교 의과대학 예방의학교실) ;
  • 홍영습 (동아대학교 의과대학 예방의학교실)
  • Published : 2010.01.30
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Abstract

This study investigated cut-off values of body mass index (BMI) and body fat measures for metabolic syndrome (MS) in elderly Koreas. Questionnaire surveys, anthropometric measurements, medical examinations, and body composition analyses were conducted for 10,077 subjects aged 40-65 years in the health examinee cohort in Korea between 2004 and 2006. Cut-off values were identified using receiver-operating characteristic (ROC) curve analysis for both men and women. Stratified analyses by weight range (<60, 60-69, 70-79, and 80-89, ${\geq}90\;kg$ for men; <50, 50-59, 60-69, 70-79, ${\geq}80\;kg$ for women) were conducted. Among male subjects, the cut-off points were $25.5\;kg/m^2$ for BMI with a sensitivity of 70.0% and a specificity of 72.0%, and 26.1% for body fat percentage with a sensitivity of 60.6% and a specificity of 76.4%. Among female subjects, the cutoff points were $24.1\;kg/m^2$ for BMI with a sensitivity of 73.3% and a specificity of 68.8%, and 31.5% for body fat percentage with a sensitivity of 76.7% and a specificity of 65.6%. Stratified analysis by weight range showed that the cutoff points of BMI and body fat measures tended to higher as weight level increased. The results of our study suggest cut-off values of BMI and body fat measure for MS were similar to the general obesity criteria in Korea.

본 연구는 단면조사 연구로 건강검진 수진자 코호트 연구에 참여하는 전국의 10개 의료기관에서 수진한 40세에서 65세 사이의 성인 남녀 10,077명을 대상으로 수행하였다. 연구대상자들에 대해 설문조사, 신체계측, 임상검사 및 체성분 분석을 시행하였고, 대사증후군의 진단에서 ROC 곡선을 이용하여 각 남녀의 체중별 체질량지수와 체성분 분석 결과의 진단적 가치를 비교하였다. 남성 대상자의 대사증후군 진단은 체질량지수 $25.5\;kg/m^2$ 임계점에서 민감도 70.0%, 특이도 72.0%로 나타났으며 26.1%의 비만기준에서는 민감도 60.6%, 특이도 76.4%였다. 여성 대상자의 경우는 체질량지수 $24.1\;kg/m^2$ 기준으로 민감도 73.3%, 특이도 68.8%였고 31.5%의 비만기준에서는 민감도 76.7%, 특이도 65.6%로 나왔다. 본 연구를 통해 전체 남녀 연구대상자의 대사증후군 진단에서 체중 증가에 따른 체질량지수와 체성분 분석결과의 임계점이 증가하는 양상을 확인하였고, 한국의 일반적 비만기준과 유사한 결과를 보였다. 이러한 결과들은 대사증후군의 진단에서 체성분 분석 결과, 체질량지수의 성별, 체중별 진단적 가치 비교와 대사증후군의 진단에 따른 각각의 임계점은 대사증후군 선별검사의 임상적인 지표로 활용될 수 있을 것으로 사료된다.

Keywords

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