한국수산과학회지 (Korean Journal of Fisheries and Aquatic Sciences)

  • 제43권6호
  • /
  • Pages.629-636
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  • 2010
  • /
  • 0374-8111(pISSN)
  • /
  • 2287-8815(eISSN)
한국수산과학회 (The Korean Society of Fisheries and Aquatic Science)
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수산물 중 penicillin계열 항생제의 분석

Analysis of Penicillin Antibiotics in Aquatic Products

  • 배진한 (국립수산물품질검사원 부산지원) ;
  • 김보미 (국립수산물품질검사원 부산지원) ;
  • 최미선 (국립수산물품질검사원 부산지원) ;
  • 노혜진 (국립수산물품질검사원 부산지원) ;
  • 박미정 (국립수산물품질검사원 부산지원)
  • Bae, Jin-Han (Busan branch, National Fisheries Products Quality Inspection Service) ;
  • Kim, Bo-Mi (Busan branch, National Fisheries Products Quality Inspection Service) ;
  • Choi, Mi-Sun (Busan branch, National Fisheries Products Quality Inspection Service) ;
  • Roh, Hye-Jin (Busan branch, National Fisheries Products Quality Inspection Service) ;
  • Park, Mi-Jung (Busan branch, National Fisheries Products Quality Inspection Service)
  • 투고 : 2010.09.14
  • 심사 : 2010.10.20
  • 발행 : 2010.12.31
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초록

A simple, rapid method for determining amoxicillin (AMO) and ampicillin (AMP) in aquatic products (flatfish, salmon, shrimp, tilapia, and yellow croaker) was evaluated. For quantification, the AMO and AMP ions at m/z 348.9 and 105.9, respectively, were selected. The limit of detection (LOD) and limit of quantification (LOQ) for detecting AMO were 0.09 and $0.25\;{\mu}g/L$, respectively. The respective values for AMP were 0.02 and $0.05\;{\mu}g/L$. After $100\;{\mu}g/L$ AMO treatment, the level decreased 10% after 7 days at $5^{\circ}C$, while it decreased 20% at $25^{\circ}C$. After 7 days, 94.9.100% of $100\;{\mu}g/L$ AMP remained after storage at $5^{\circ}C$, while 62.3.100% remained after storage at $25^{\circ}C$. Using the food code method, the recovery of AMO ranged from 64.1.92.0% and that of AMP from 44.8.86.2%. With a protein centrifugation method, the recovery of AMO ranged from 39.8.87.9% and that of AMP from 78.0.98.1%. With liquid-liquid extraction, the recovery of AMO ranged from 36.5.88.3% and that of AMP from 31.8.75.1%.

키워드

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피인용 문헌

  1. Residues of ampicillin in blood of cultured olive flounder by oral, injection and dipping administration vol.25, pp.3, 2012, https://doi.org/10.7847/jfp.2012.25.3.211
  2. 인천 유통 수산물 중 잔류동물용의약품 조사 vol.44, pp.5, 2018, https://doi.org/10.5668/jehs.2018.44.5.444