Analysis of Mineral Contents in Tissues and Bone Mineral Density of Rats

흰쥐의 조직 중 무기질 함량과 골밀도 분석

  • Kim, Myung-Hee (Dept. of Food and Nutrition, Kongju National University) ;
  • Kim, Moo-Kyung (Dept. of Food and Nutrition, Kongju National University) ;
  • Lee, Jong-Wan (Dept. of Animal Resources Science, Kongju National University) ;
  • Kim, Mi-Hyun (Dept. of Food and Nutrition, Kangwon National University) ;
  • Kang, Myung-Hwa (Dept. of Food Science and Nutrition, Hoseo University) ;
  • Choi, Mi-Kyeong (Dept. of Food and Nutrition, Kongju National University)
  • 김명희 (공주대학교 식품영양학과) ;
  • 김무경 (공주대학교 식품영양학과) ;
  • 이종완 (공주대학교 동물자원학과) ;
  • 김미현 (강원대학교 식품영양학과) ;
  • 강명화 (호서대학교 식품영양학과) ;
  • 최미경 (공주대학교 식품영양학과)
  • Received : 2005.05.20
  • Accepted : 2010.08.20
  • Published : 2010.09.30


The purpose of present study was to analyze mineral contents in various tissues and investigate theirs relation with bone mineral density (BMD) in rats. Fifteen Sprague-Dawley rats were fed standard diet for 4 weeks. Body weight gain, feed intake, and feed efficiency ratio were 41.00 g/week, 171.15 g/week, and 0.24 respectively. Among 12 minerals in serum, Ca is the highest with 6.86 mg/dl. Serum Mg, Se, and Cu were 2.52 mg/dl, 0.23 mg/dl and 0.22 mg/dl respectively. Mg contents in liver, spleen, and kidney were $246.36\;{\mu}/g$, $105.01\;{\mu}/g$, and $273.38\;{\mu}/g$ respectively. Tibia contents of Ca, Mg, Zn, Fe and V were 194.91 mg/g, 23.10 mg/g, 0.60 mg/g, 0.35 mg/g and 0.14 mg/g respectively. BMDs of right tibia and spine were 122.04 mg/cm and $153.61\;mg/cm^2$. There were significantly positive correlations between tibia BMD and Se (p<0.05), tibia BMD and V (p<0.01), spinal BMD and V(p<0.05), respectively. It's expected that these results are used as a reference data in following study to elucidate physiological function of minerals.



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