Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Saponin Contents and Physicochemical Properties of Red Ginseng Extract Pouch Products Collected from Ginseng Markets in Korea

국내 인삼시장에서 유통되고 있는 홍삼 파우치 제품의 사포닌 함량 및 이화학적 특성

  • Choi, Jae-Eul (College of Agriculture & Life Science, Chungnam National University) ;
  • Han, Jin-Soo (College of Agriculture & Life Science, Chungnam National University) ;
  • Kang, Sun-Joo (College of Agriculture & Life Science, Chungnam National University) ;
  • Kim, Kwan-Hou (Geumsan Ginseng & Medicinal Crop Experiment Station, CNARES) ;
  • Kim, Kyoung-Hee (Dept. of Food and Nutrition, Chungnam National University) ;
  • Yook, Hong-Sun (Dept. of Food and Nutrition, Chungnam National University)
  • 최재을 (충남대학교 농업생명과학대학) ;
  • 한진수 (충남대학교 농업생명과학대학) ;
  • 강선주 (충남대학교 농업생명과학대학) ;
  • 김관후 (충남농업기술원 금산약초시험장) ;
  • 김경희 (충남대학교 식품영양학과) ;
  • 육홍선 (충남대학교 식품영양학과)
  • Received : 2010.07.06
  • Accepted : 2010.10.18
  • Published : 2010.11.30
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Abstract

To obtain data for the standardization of manufacturing method of red ginseng extract pouch products, saponin and physico-chemical properties of 44 Korean red ginseng extract pouch products were analyzed. The concentration of total ginsenoside contents were 5.5~185.7 mg/100 mL. Distribution of the contents of ginsenoside $Rg_3$, $Rg_2$, $Rh_1$, and $Rh_2$ known to have anticancer effect are as follows: $Rg_3$ is 1.6~46.3 mg/100 mL, $Rg_2$ is 0~22.0 mg/100 mL, $Rh_1$ is 0~4.3 mg/100 mL and that of $Rh_2$ is 0~20.4 mg/100 mL, respectively. The anti-diabetic effect of ginsenoside $Rb_2$ and Re distribution of contents were 0~10.8 mg/100 mL and 0~7.0 mg/100 mL, respectively. Among the other saponins, exhibited content to distribution of ginsenoside $Rb_1$ was 0~25.2 mg/100 mL, Rc was 0~12.5 mg/100 mL, Rd was 0~11.3 mg/100 mL, Rf was 0~5.9 mg/100 mL and $Rg_1$ was 0~4.4 mg/100 mL. Results of physicochemical characterization showed total sugar content of 226.6~3,102.9 mg/100 mL, total soluble solids content $1.4\sim9.5^{\circ}Bx$, turbidity 82.2~100.0%, pH in the range of 4.1 to 5.0, respectively. In approximately 50% of collected domestic ginseng extract pouch products (21~24 items), ginsenoside $Rb_1$, $Rb_2$, Rc, Rd, Re and $Rg_1$ were not detected, and saponin content of each product appears to differ greatly. Results indicated that standardization of production methods and standards set for red ginseng extract pouch products in Korea is needed.

홍삼 파우치 제품의 성분 및 제조방법의 표준화를 위한 일환으로 국내 유통 중인 홍삼 파우치의 사포닌 함량 및 이화학적 특성을 분석하였다. 총 ginsenoside 함량은 5.5~185.7 mg/100 mL의 함량을 나타내었고 항암효과로 알려진 ginsenoside $Rg_3$, $Rg_2$, $Rh_1$과 $Rh_2$의 함량 분포는 $Rg_3$는 1.6~46.3 mg/100 mL, $Rg_2$는 미검출~22.0 mg/100 mL, $Rh_1$은 미검출~4.3 mg/100 mL, $Rh_2$는 미검출~20.4 mg/100 mL의 분포를 나타내었다. 항 당뇨 효과가 있는 ginsenoside $Rb_2$와 Re의 함량분포는 $Rb_2$는 미검출~10.8 mg/100 mL, Re는 미검출~7.0 mg/100 mL의 함량을 나타내었으며 그 밖의 사포닌 중 ginsenoside $Rb_1$는 미검출~25.2 mg/100 mL, Rc는 미검출~12.5 mg/100 mL, Rd는 미검출~11.3 mg/100 mL, Rf는 미검출~5.9 mg/100 mL, $Rg_1$는 미검출~4.4 mg/100 mL까지의 함량 분포를 보였다. 이화학적 특성 분석결과 총당함량은 226.6~3,102.9 mg/100 mL, 당도는 $1.4\sim9.5^{\circ}Bx$, 탁도는 82.2~100.0%, pH는 4.1~5.0의 범위를 나타내었다. 국내에서 수집한 홍삼 파우치 제품의 약 50%(21~24개 제품)가 ginsenoside $Rb_1$, $Rb_2$, Rc, Rd, Re, $Rg_1$이 미검출 되었으며, 각 제품별 사포닌 함량 차이가 매우 크게 나타나, 국내유통 중인 홍삼 제품에 대한 기준 설정 및 생산방법의 표준화가 필요할 것으로 사료된다.

Keywords

References

  1. Yokozawa T, Kobayashi T, Oura H, Kawashima Y. 1985. Studies on the mechanism of the hypoglycemic activity of ginsenoside-$Rb_2$ in streptozotocin-diabetic rats. Chem Pharm Bull 33: 869-872. https://doi.org/10.1248/cpb.33.869
  2. Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L, Dey L, Pugh W, Rue PA, Polonsky KS, Yuan CS. 2002. Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes 51: 1851-1858. https://doi.org/10.2337/diabetes.51.6.1851
  3. Xie JT, Mehendale SR, Li XM, Quigg R, Wang XY, Wang CZ, Wu JA, Aung HH, Rue PA, Bell GI, Yuan CS. 2005. Anti-diabetic effect of ginsenoside Re in ob/ob mice. Biochim Biophy Acta 1740: 319-325. https://doi.org/10.1016/j.bbadis.2004.10.010
  4. Lee SY, Kim GT, Roh SH, Song JS, Kim HJ, Hong SS, Kwon SW, Park JH. 2009. Proteomic analysis of the anti-cancer effect of 20S-ginsenoside $Rg_3$ in human colon cancer cell lines. Biosci Biotechnol Biochem 73: 811-816. https://doi.org/10.1271/bbb.80637
  5. Cho WC, Chung WS, Lee SK, Leung AW, Cheng CH, Yue KK. 2006. Ginsenoside Re of Panax ginseng possesses significant antioxidant and antihyperlipidemic efficacies in streptozotocin-induced diabetic rats. European J Pharmacol 550: 173-179. https://doi.org/10.1016/j.ejphar.2006.08.056
  6. Tang WY, Zhang Y, Gao J, Ding XY, Gao S. 2008. The anti-fatigue effect of 20(R)-ginsenoside $Rg_3$ in mice by intranasally administration. Biol Pharm Bull 31: 2024-2027. https://doi.org/10.1248/bpb.31.2024
  7. Jung IK, Lee SY, Park IH, Cheong JH. 2005. Anti-stress activities of ginsenoside $Rb_1$ is related with GABAnergic neuron. J Appl Pharmacol 13: 165-173. https://doi.org/10.4062/biomolther.2005.13.3.165
  8. Cheng Y, Shen LH, Zhang JT. 2005. Anti-amnestic and anti-aging effects of ginsenoside $Rg_1$ and $Rb_1$ and its mechanism of action. Acta Pharmacol Sin 26: 143-149. https://doi.org/10.1111/j.1745-7254.2005.00034.x
  9. Choi JE, Nam KY, Li XG, Kim HH, Cho HS, Hwang KB, Ko SK. 2008. Changes of surface color formation and constituents of white ginseng prepared with peeling by using barker. Korean J Crop Sci 53: 369-375.
  10. Kim MJ, Li XG, Han JS, Lee SE, Choi JE. 2009. Effect of blue and red LED irradiation on growth characteristics and saponin contents in Panax ginseng C. A. Meyer. J Korean Med Sci 17: 187-191.
  11. Yun TK, Lee YS, Lee YH, Yun HY. 2001. Cancer chemopreventive compounds of red ginseng produced from Panax ginseng C. A. Meyer. J Ginseng Res 25: 107-111.
  12. Keum YS, Park KK, Lee JM, Chun KS, Park JH, Lee SK, Kwon H, Surh YJ. 2000. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng. Cancer Lett 150: 41-48. https://doi.org/10.1016/S0304-3835(99)00369-9
  13. Kim DH, Kwak KH, Lee KJ, Kim SJ. 2004. Effects of Korea red ginseng total saponin on repeated unpredictable stress 260 induced changes of proliferation of neural progenitor cells and BDNF mRNA expression in adult rat hippocampus. J Ginseng Res 28: 94-103. https://doi.org/10.5142/JGR.2004.28.2.094
  14. Petkov VD, Mosharrof AH. 1987. Effects of standardized ginseng extract on learning, memory and physical capabilities. Am J Chin Med 15: 19-29. https://doi.org/10.1142/S0192415X87000047
  15. Bae KC, Kim SH. 1998. Antioxidant effects of Korea ginseng radix, Korea red ginseng radix and total saponin. Korean J Orient Med Path 12: 72-81.
  16. Kim YM, Yoon CE, Kim KH, Lee EW. 2007. Studies on saprogenic bacteria isolated from Korean red ginseng extract product. J Life Sci 17: 1394-1399. https://doi.org/10.5352/JLS.2007.17.10.1394
  17. Han JS, Li XG, Park YJ, Kang SJ, Nam KY, Choi JE. 2009. Effects of extraction temperature and time on saponin content an quality in raw ginseng (Panax ginseng) water extract. J Korean Med Sci 17: 352-356.
  18. Hu JN, Lee JH, Shin JA, Choi JE, Lee KT. 2008. Determination of ginsenosides content in Korean ginseng seeds and roots by high performance liquid chromatography. Food Sci Biotechnol 17: 430-433.
  19. Miller GL. 1959. Use of dinitrosalicylic acid reagent for determination of reducing sugar. Anal Chem 31: 426-428. https://doi.org/10.1021/ac60147a030
  20. Li XG, Han JS, Park YJ, Kang SJ, Kim JS, Nam KY, Lee KT, Choi JE. 2009. Extracting conditions for promoting ginsenoside contents and taste of red ginseng water extract. Korean J Crop Sci 54: 287-293.
  21. Lee HL, Kang JI, Lee SY. 2008. Saponin composition and physicochemical properties of Korean red ginseng extract as affected by extracting conditions. J Korean Soc Food Sci Nutr 37: 256-260. https://doi.org/10.3746/jkfn.2008.37.2.256

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