Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Canine Distemper Virus Neutralizing Antibodies of Adult Dogs in Korea

국내 성견의 개 디스템퍼 바이러스에 대한 중화항체가 조사

  • Jeoung, Seok-Young (School of Veterinary Medicine & Institute of Veterinary Science Kangwon National University) ;
  • Ahn, So-Jeo (School of Veterinary Medicine & Institute of Veterinary Science Kangwon National University) ;
  • Chang, Kwon-Sik (School of Veterinary Medicine & Institute of Veterinary Science Kangwon National University) ;
  • Pak, Son-Il (School of Veterinary Medicine & Institute of Veterinary Science Kangwon National University) ;
  • Kim, Doo (School of Veterinary Medicine & Institute of Veterinary Science Kangwon National University)
  • 정석영 (강원대학교 수의학부대학 및 동물의학연구소) ;
  • 안소저 (강원대학교 수의학부대학 및 동물의학연구소) ;
  • 장권식 (강원대학교 수의학부대학 및 동물의학연구소) ;
  • 박선일 (강원대학교 수의학부대학 및 동물의학연구소) ;
  • 김두 (강원대학교 수의학부대학 및 동물의학연구소)
  • Published : 2009.10.31
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Abstract

There were outbreaks of canine distemper in Korea from the late 1990's to the early 2000's even though modified live CDV vaccines had been used as the same way as before. The present study was undertaken to investigate the levels of neutralizing antibodies in the Korean dog population, and the factors associated with the levels, with special reference to the vaccination history of the dogs. A total of 772 serum samples were from clinically healthy dogs with over one year old throughout the Korea from January 2003 to April 2004. Details on the sex, breed, age, vaccination status and disease histories were recorded. The level of neutralizing antibodies titer was determined with a modified version of the microneutralization test. Titers over 16 were classified as protective CDV antibody titers. The overall rate of adult dogs with protective antibody titers was 96.0%. The dogs with protective antibody titers varied depending on age, sex, rearing environment and vaccination status. Because the majority of healthy adult dogs in Korea had adequate serum antibody titers against CDV and the immunity provided by the vaccinations is claimed to last for several years, annual revaccination protocol for CDV in adult dogs should be reconsidered.

Keywords

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