Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Acute Eosinophilic Pneumonia Associated with Intramuscular Administration of Progesterone Following In Vitro Fertilization

체외수정 시술 후 프로게스테론 근육주사와 연관된 급성 호산구성 폐렴 1예

  • Park, Sung Keun (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Choi, Byoung Ho (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Chon, Su Yeon (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Kim, Yu Jin (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Kyung, Sun Young (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Lee, Sang Pyo (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Jeong, Sung Hwan (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Park, Jeong-Woong (Department of Internal Medicine, Gachon University of Medicine and Science)
  • 박성근 (가천의과학대학교 내과학교실) ;
  • 최병호 (가천의과학대학교 내과학교실) ;
  • 전수연 (가천의과학대학교 내과학교실) ;
  • 김유진 (가천의과학대학교 내과학교실) ;
  • 경선영 (가천의과학대학교 내과학교실) ;
  • 이상표 (가천의과학대학교 내과학교실) ;
  • 정성환 (가천의과학대학교 내과학교실) ;
  • 박정웅 (가천의과학대학교 내과학교실)
  • Received : 2009.08.12
  • Accepted : 2009.10.01
  • Published : 2009.12.30
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Abstract

Acute eosinophilic pneumonia (AEP) is characterized by idiopathic acute febrile illness, diffuse pulmonary infiltration, severe hypoxemia, and pulmonary eosinophilia. We report a case of AEP associated with intramuscular administration of progesterone as luteal phase support after in vitro fertilization. A 33-year-old woman presented to our emergency room with tachypnea and hypoxemia, complaining of fever and cough for 4 days, and dyspnea for 2 days. The symptoms began 9 days after the first injection of progesterone. Chest radiograph showed bilateral infiltrates, located predominantly in the periphery of the lungs, with blunting of the costophrenic angle. Symptoms and chest radiograph dramatically improved after corticosteroid therapy and shifting the progesterone from an intramuscular form of administration to a vaginal form of administration.

Keywords

References

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