위선암에서 발견된 칸디다증 1예

Candida Infection in a Patient with Gastric Carcinoma; 1 Case Report

  • 정주원 (가톨릭대학교 의과대학 외과학교실) ;
  • 유창영 (가톨릭대학교 의과대학 병원병리학교실) ;
  • 정대영 (가톨릭대학교 의과대학 내과학교실) ;
  • 허훈 (가톨릭대학교 의과대학 외과학교실) ;
  • 전해명 (가톨릭대학교 의과대학 외과학교실)
  • Chyung, Ju-Won (Department of Surgery, College of Medicine, The Catholic University of Korea) ;
  • Yoo, Chang-Young (Department of Hospital Pathology, College of Medicine, The Catholic University of Korea) ;
  • Cheung, Dae-Young (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Hur, Hoon (Department of Surgery, College of Medicine, The Catholic University of Korea) ;
  • Jeon, Hae-Myung (Department of Surgery, College of Medicine, The Catholic University of Korea)
  • 투고 : 2008.11.19
  • 심사 : 2009.03.25
  • 발행 : 2009.03.31

초록

위장관 칸디다증은 대개는 면역성이 저하된 경우에 기회 감염으로 발현되는 것이 일반적이다. 위장관 칸디다증 중식도 칸디다증이 가장 많은 빈도를 차지하고 있고 주로 면역기능이 억제된 환자에서 잘 발생하지만 드물게 건강한 성인에서도 보고된다. 현재까지는 양성 위궤양에 병발된 위장관 칸디다증이 흔히 보고되었지만 위선암에서 발견된 칸디다증은 비교적 드물다. 저자들은 속쓰림과 소화불량을 주소로 내원한 72세 여자환자에서 수술전 위선암과 칸디다증으로 진단되어 fluconazole을 경구투여를 통하여 칸디다증을 치료한 후 위전절제술을 시행한 증례를 경험하였다. 본 증례의 경험과 문헌 검색을 통하여, 저자들은 위암 수술 전 위암과 함께 위 칸디다증을 진단받은 환자에 대하여 칸디다에 대한 약물 치료 후 수술을 권유하는 바이다.

Most gastric candida infections have been reported in immune-insufficient patients with peptic ulcer, but there have been few reports on gastric candidiasis with malignant ulcer in the stomach. We experienced a case of candida infection with gastric carcinoma in a 72-year-old female with diabetic mellitus. The endoscopic view showed multiple whitish necrotic plaques with a huge ulcer in the body of the stomach. The pathologic findings showed that budding yeast and pseudohyphae had infiltrated through the ulcerated stomach wall and the stomach wall contained tubular adenocarcinoma. After treatment with Fluconazole medication for 14 days, the patient underwent total gastrectomy along with D2 lymph node dissection. For the final pathologic results, there was no evidence of any remnant candidiasis, and the patient was discharged without specific complications. Through our experience and with reviewing articles about gastric candidiasis, we recommend that the gastric candidiasis that is accompanied with gastric malignancy should be treated before administering definite treatments for the gastric cancer.

키워드

참고문헌

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