Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Effects of the Sarcodon aspratus on the High Level of Blood Lipid and Obesity Induced by High Fat-diet in Rat

능이 버섯이 고지방식이에 의한 고지혈증 비만 쥐에 미치는 영향

  • Lee, Kyung-Suk (Department of Biology, The Graduate School, Catholic University of Daegu) ;
  • Kim, Jong-Bong (Department of Biology, The Graduate School, Catholic University of Daegu)
  • 이경숙 (대구가톨릭대학교 대학원 생물학과) ;
  • 김종봉 (대구가톨릭대학교 대학원 생물학과)
  • Published : 2009.09.30
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Abstract

The mushroom, Sarcodon aspratus was tested for its possibility of being a health food against corpulence. The mushroom powder was fed to rats with high-fat diet-induced corpulence for 6 weeks. To measure its effects, various factors such as obesity index, serum lipid, and organ weight were analyzed and compared. The group fed a high-fat diet showed a significant increase in the levels of triglyceride, total cholesterol and LDL-cholesterol in serum. However, this increase was not shown in the group fed mushroom powder. The R$\ddot{o}$hrer index (one of many obesity indexes) was higher in the group fed a high-fat diet compared to that of control group. However, there was a significant decrease in the R$\ddot{o}$hrer index in the group fed with mushroom powder. Especially, the increased ratio of liver to body weight was observed in the group fed a high-fat diet compared to the control group. These results suggest that the significant changes in obesity index and organ weight in the group fed with mushroom powder are due to the decreased level of serum triglyceride. Thus, there is a possibility for Sarcodan aspratus to become a heath food that can prevent diseases related to corpulence.

능이버섯의 항비만 건강식품으로서의 이용가능성을 분석하였다. 고지방식이에 의해 유도된 비만쥐에 6주 동안 능이버섯 분말을 섭취시켜, 능이버섯의 효과를 알아보기 위하여 비만지수, 혈청지질, 장기무게 등의 여러 가지 요인들을 분석하였다. 고지방식이를 먹인 쥐 혈청의 중성지방, 총콜레스테롤 및 Ldl은 유의적으로 증가하였으나 능이버섯분말을 먹인 쥐는 증가하지 않았다. 고지방식이 쥐에서 R$\ddot{o}$hrer index는 대조군에 비해 유의적으로 증가하였으나 버섯 분말을 섭취한 쥐는 R$\ddot{o}$hrer index가 유의적으로 감소하였다. 특히 몸무게에 대한 간 무게의 비율은 대조군에 비해 비만식이 쥐에서 높았다. 이러한 결과들은 버섯을 먹인 쥐에서의 비만지수와 장기무게의 유의적인 변화는 혈청에서 중성지방의 감소 때문인 것으로 생각된다. 그렇기 때문에 능이버섯은 비만과 관련된 질병을 막을 수 있는 건강식품의 하나로 이용 될 수 있는 가능성이 있다.

Keywords

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