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Ultrashort Pulsed Laser Machining for Biomolecule Trapping

  • Choi, Hae-Woon (School of Mechanical and Automotive Engineering, Keimyung University) ;
  • Farson, Dave F. (Laboratory for Multiscale Processing & Characterization, The Ohio State University) ;
  • Lee, L.James (Department of Chemical and Biomolecular Engineering, The Ohio State University) ;
  • Lee, Ho (School of Mechanical Engineering, Kyungpook National University)
  • 투고 : 2009.06.26
  • 심사 : 2009.09.14
  • 발행 : 2009.09.25

초록

Ultrashort pulse laser drilling of polycarbonate track-etched membrane (pTEM) material was used to fabricate a mouse embryo cell trapping device. Holes with a diameter of $2{\mu}m$ to $5{\mu}m$ were fabricated on a $10{\mu}m$ thick membrane using a femtosecond laser with a 150 fs pulse width and 775 nm wavelength and multiple-pulse irradiation. In cell trapping tests, the overall cell occupancy of the machined holes in the fabricated pTEM was found to be more than 80%. The results of a single pulse and multiple pulse irradiation were compared in terms of the surface quality. It was generally found that a single pulse with high energy was less desirable than irradiation with multiple pulses of lower energy.

키워드

참고문헌

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피인용 문헌

  1. Wettability modification of electrospun poly(ɛ-caprolactone) fibers by femtosecond laser irradiation in different gas atmospheres vol.257, pp.8, 2011, https://doi.org/10.1016/j.apsusc.2010.11.072